Results 11 to 20 of about 127,419 (262)
Acquired bleeding disorders [PDF]
Haemophilia, 2020 AbstractAcquired bleeding disorders can accompany hematological, neoplastic, autoimmune, cardiovascular or liver diseases, but can sometimes also arise spontaneously. They can manifest as single factor deficiencies or as complex hemostatic abnormalities. This review addresses (a) acquired hemophilia A, an autoimmune disorder characterized by inhibitory
Andreas Tiede +2 more
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Haemophilia, 2006 Summary. Deficiencies of coagulation factors other than factor VIII and factor IX (afibrinogenemia, FII, FV, FV+FVIII, FVII, FX, FXI, FXIII) that cause bleeding disorders (RBDs) are inherited as autosomal recessive traits and are rare, with prevalences in the general population varying between 1 in 500.000 and 1 in 2 million for the homozygous forms ...
Peyvandi, F. +9 more
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Haemophilia, 2012 Summary. Rare bleeding disorders (RBDs) include the inherited deficiencies of fibrinogen, factor (F)II, FV, FV+FVIII, FVII, FX, FXI and FXIII. There have been remarkable advances in understanding the molecular profiles that lead to each type of coagulation factor deficiency.
F. Peyvandi +3 more
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Epistaxis in a Pediatric Outpatient Clinic: Could It be an Alarming Sign?
International Archives of Otorhinolaryngology, 2022 Introduction Epistaxis is a common presentation among children. Objective To investigate the suitability of a simple tool of assessment for patients with epistaxis that could guide in subgrouping those with possible bleeding tendencies who may
Mohsen Saleh ElAlfy +5 more
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Predictors of quality of life among adolescents and young adults with a bleeding disorder
Health and Quality of Life Outcomes, 2017 Background Health-related quality of life (HRQoL) in adolescents and young adults with bleeding disorders is under-researched. We aimed to describe factors related to HRQoL in adolescents and young adults with hemophilia A or B or von Willebrand disease.
John M. McLaughlin +5 more
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Bernard–Soulier syndrome and anesthetic management
MRIMS Journal of Health Sciences, 2020 Bernard–Soulier syndrome (BSS) is a rare autosomal recessive disease with bleeding diathesis due to platelet dysfunction secondary to the absence of the von Willebrand factor receptor on the platelet surface called glycoprotein Ib–V–IX.
Manjula Venkatesh Ramsali +5 more
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A Novel Deletion Mutation of the F8 Gene for Hemophilia A
Diagnostics, 2022 Background: Hemophilia A (HA) is an X-linked recessive blood coagulation disorder caused by a variety of abnormalities in F8 gene, resulting in the absence of impaired molecule production of factor VIII (FVIII) in the plasma.
Jingwei Wang +8 more
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Isolated scalp hematoma: An unusual presentation of congenital afibrinogenemia
Indian Pediatrics Case Reports, 2023 Background: Congenital fibrinogen disorder is a rare autosomal recessive blood coagulation disorder, where majority of patients present with bleeding, whereas a few may paradoxically develop thrombosis.
Arnab Ghorui +2 more
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Genomics of bleeding disorders [PDF]
Haemophilia, 2014 SummaryMolecular genetic tools are widely applied in inherited bleeding disorders. New genes involved in haemorrhagic disorders have been identified by genome wide linkage analysis on families with a specific phenotype. LMNA1 or MCFD in combined FV/FVIII‐deficiency and VKORC1 in vitamin K coagulation factor deficiency type 2 are two examples ...
A C, Goodeve, A, Pavlova, J, Oldenburg
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Journal of Family Medicine and Primary Care, 2022 Factor VII deficiency is a rare bleeding disorder showing an autosomal recessive pattern of inheritance. Data from our country on this particular entity is lacking.
Mimi Ganguly +4 more
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