Results 1 to 10 of about 1,666,748 (304)
The Bleeding Disorders Research Collaborative [PDF]
Blood Vessels, Thrombosis & Hemostasis: The Bleeding Disorders Research Collaborative (BDRC) aims to advance an accessible standard of care and quality of life for all people living with inheritable bleeding disorders.
Leonard A. Valentino +8 more
doaj +2 more sources
Women and bleeding disorders [PDF]
Haemophilia, 2010 Summary. While women are rarely affected by haemophilia, they are equally as likely as men to have other bleeding disorders. Menorrhagia, or heavy menstrual bleeding, is the most common symptom that they experience. Not only is menorrhagia more prevalent among women with bleeding disorders, but bleeding disorders are more prevalent among women with ...
exaly +3 more sources
Acquired bleeding disorders [PDF]
Haemophilia, 2020 AbstractAcquired bleeding disorders can accompany hematological, neoplastic, autoimmune, cardiovascular or liver diseases, but can sometimes also arise spontaneously. They can manifest as single factor deficiencies or as complex hemostatic abnormalities. This review addresses (a) acquired hemophilia A, an autoimmune disorder characterized by inhibitory
Andreas Tiede +2 more
openaire +7 more sources
Gene transfer in hemophilia B: a big step forward
Bleeding, Thrombosis and Vascular Biology, 2023 Not ...
Giancarlo Castaman
doaj +3 more sources
Psychosocial burden of type 1 and 2 hereditary angioedema: a single-center Canadian cohort study
Allergy, Asthma & Clinical Immunology, 2021 Background Hereditary angioedema (HAE) is a rare but serious disorder associated with a multifaceted burden of illness including a high prevalence of psychiatric symptoms and impaired health-related quality of life (HRQoL).
Julia Hews-Girard, Marilyn Dawn Goodyear
doaj +1 more source
Haemophilia, 2006 Summary. Deficiencies of coagulation factors other than factor VIII and factor IX (afibrinogenemia, FII, FV, FV+FVIII, FVII, FX, FXI, FXIII) that cause bleeding disorders (RBDs) are inherited as autosomal recessive traits and are rare, with prevalences in the general population varying between 1 in 500.000 and 1 in 2 million for the homozygous forms ...
Peyvandi, F. +9 more
openaire +3 more sources
Haemophilia, 2012 Summary. Rare bleeding disorders (RBDs) include the inherited deficiencies of fibrinogen, factor (F)II, FV, FV+FVIII, FVII, FX, FXI and FXIII. There have been remarkable advances in understanding the molecular profiles that lead to each type of coagulation factor deficiency.
F. Peyvandi +3 more
openaire +2 more sources
Research and Practice in Thrombosis and Haemostasis, 2022 Background Goal Attainment Scaling for Hemophilia (GOAL‐Hēm) is a novel, hemophilia‐specific, validated patient engagement tool and patient‐reported outcome instrument.
Jonathan C. Roberts +6 more
doaj +1 more source
Genomics of bleeding disorders [PDF]
Haemophilia, 2014 SummaryMolecular genetic tools are widely applied in inherited bleeding disorders. New genes involved in haemorrhagic disorders have been identified by genome wide linkage analysis on families with a specific phenotype. LMNA1 or MCFD in combined FV/FVIII‐deficiency and VKORC1 in vitamin K coagulation factor deficiency type 2 are two examples ...
A C, Goodeve, A, Pavlova, J, Oldenburg
openaire +2 more sources
Women with bleeding disorders [PDF]
Haemophilia, 2018 Diagnosis of the genetic status and assessment of potential clotting factor deficiency in haemophilia carriers are performed more easily nowadays. However, delays in providing those diagnosis and appropriate management are often reported despite increased availability of genetic techniques and improved awareness that carriers may have bleeding ...
C. Hermans, R. Kulkarni
openaire +2 more sources