Results 41 to 50 of about 4,310,557 (239)

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Can capacity limitations in primary care undergraduate placements be addressed using a blended learning approach?

, 2023
Description and evaluation of introduction of blended learning for year 1 and 2 students at ...
Curtis, J., Neden, C.
core  

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

FEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page, Rachel J. Hunt, Lauren J. Albee, Daniel Berwick, Alison Snape   +4 more
wiley   +1 more source

Analysis of Home Care Supports Funded by the HSE 2008–2016 [PDF]

, 2016
This paper seeks to summarise the situation of publicly funded home care over the period 2008- 2016. Of particular interest is the overall change to the level of resources being directed to home care in the 2016 HSE Service Plan, in particular the actual
Care Alliance Ireland
core  

Ethical Foreground and Background in Adult Educator Work

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley   +1 more source

Attitudes and Expectations Towards Mental Health Interventions in the General Population: Comparing Face-to-Face Counseling, Blended Counseling, and Digital or On-Paper Self-Help

Clinical Psychology in Europe
[Background] Digital interventions are supported by a growing evidence base and have the potential to contribute to accessible and personalized mental healthcare services.
Nele A. J. De Witte, Fien Buelens, Jennifer Apolinário-Hagen, Tom Van Daele   +3 more
doaj   +1 more source

Blended care vs. usual care in the treatment of depressive symptoms and disorders in general practice [BLENDING]: study protocol of a non-inferiority randomized trial

BMC Psychiatry, 2017
Background The majority of patients with depressive disorders are treated by general practitioners (GPs) and are prescribed antidepressant medication. Patients prefer psychological treatments but they are under-used, mainly due to time constraints and ...
Btissame Massoudi, Marco H. Blanker, Evelien van Valen, Hans Wouters, Claudi L. H. Bockting, Huibert Burger   +5 more
doaj   +1 more source

Comparing the effects of teach-back method, multimedia and blended training on self-care and social support in patients with heart failure: A randomized clinical trial

Journal of Education and Health Promotion, 2021
BACKGROUND: The knowledge level of caregivers and their support for patients can affect the self-care of patients with heart failure (HF). The present study was conducted to compare the effects of teach-back, multimedia, and blended training methods on ...
Maryam Karami Salaheddin Kola, Hedayat Jafari, Jamshid Yazdani Charati, Vida Shafipour   +3 more
doaj   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

My Cosmos: development, clinical protocol, and preliminary usability of a gamified transdiagnostic digital CBT platform

Frontiers in Psychiatry
BackgroundDigital cognitive–behavioural therapy (dCBT) has been shown to be effective for anxiety and depression, yet sustaining engagement remains a key challenge that limits real-world impact. Gamification and extended reality (XR) elements may support
Sasha Del Vecchio, Tommaso Barlattani, Antonino Carcione, Antonino Carcione, Francesca Pacitti, Marco Recchioni   +5 more
doaj   +1 more source