Results 101 to 110 of about 323,867 (242)

Myeloid Focal Adhesion Kinase Promotes Macrophage Accumulation but Does Not Alter Tumor Progression in Hepatocellular Carcinoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) develops within an immunologically complex tumor microenvironment that is heavily shaped by infiltrating myeloid cells. Immune‐based treatment strategies such as atezolizumab plus bevacizumab have shown promising therapeutic benefits, but patients do not experience durable responses.
Eugene Ham, Kyle Boedeker, Claudia Rose Keating, Ruisong Ye, Frankie Montalbano, Sophia Mankaruse, Xianzhong Ding, Jonathan P. Rennhack, Wei Qiu   +8 more
wiley   +1 more source

Undercomplete Blind Subspace Deconvolution

J. Mach. Learn. Res., 2007
We introduce the blind subspace deconvolution (BSSD) problem, which is the extension of both the blind source deconvolution (BSD) and the independent subspace analysis (ISA) tasks. We examine the case of the undercomplete BSSD (uBSSD). Applying temporal concatenation we reduce this problem to ISA.
Zoltán Szabó 0001, Barnabás Póczos, András Lörincz   +2 more
openaire   +3 more sources

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Blind deconvolution of second harmonic microscopy images of the living human eye. [PDF]

Biomed Opt Express, 2023
Martínez-Ojeda RM, Mugnier LM, Artal P, Bueno JM.   +3 more
europepmc   +1 more source

Unveiling Van Der Waals Forces and Associated Hamaker Constants Across the Nanomaterial Landscape With Advanced Atomic Force Microscopy

Small Methods, EarlyView.
Van der Waals interactions are reviewed through the lens of advanced atomic force microscopy, highlighting recent progress in nanoscale quantification of Hamaker constants. Emerging methodologies enable high‐resolution mapping of intermolecular forces in 2D materials and biological systems, bridging experimental measurements with quantum‐informed ...
Amir Farokh Payam, Horacio V. Guzman, Alexandre Tkatchenko   +2 more
wiley   +1 more source

Deconvolution Estimation in Measurement Error Models: The R Package decon [PDF]

Data from many scientific areas often come with measurement error. Density or distribution function estimation from contaminated data and nonparametric regression with errors in variables are two important topics in measurement error models.
Bin Wang, Xiao-Feng Wang
core  

Semi-blind fast equalisation of QAM channels using concurrent gradient-Newton CMA and soft decision-directed scheme

, 2010
This contribution considers semi-blind adaptive equalization for communication systems that employ high-throughput quadrature amplitude modulation signalling.
Chen, Sheng
core   +1 more source

A mixed single image motion deblur method

Dianzi Jishu Yingyong, 2019
The blind recovery of images is a difficult problem in the field of digital image processing. Researching the restoration of motion blurred images，a hybrid single image motion deblur method is proposed.
Wang Siyu, Li Liangrong, Gu Ping, Li Zhen   +3 more
doaj   +1 more source

Domination Versus Sisterhoods in the Blood Microbiota of Migrating Birds: Patterns of Within‐ and Between‐Individual Blood Parasite Diversity Revealed Through Metabarcoding

Integrative Zoology, EarlyView.
Avian haemosporidian blood parasites are typically identified through Sanger sequencing of a partial cytochrome b fragment, the MalAvi barcoding region. Next‐generation sequencing is seldom used for avian blood parasite identification; this study demonstrates a higher detection rate of co‐infections via metabarcoding and its possible implications ...
Peter Pibaque, Gaia Porporato, Simone Cescutti, Alanis Cruz‐Flores, Tobias Busche, Anika Winker, Tim Maximilian Rapp, Patrick Bergkamp, Anna Doneva, Nayden Chakarov   +9 more
wiley   +1 more source

Distinct Skin Penetration and Immune Responses to Ionic and Nanoparticulate Cobalt in Allergic Contact Dermatitis

Allergy, EarlyView.
Cobalt chloride (CoCl2) and cobalt nanoparticles (CoNPs) induce a shared, severity‐dependent inflammatory response in cobalt‐sensitized skin characterized by activation of interferon signaling, inflammatory pathways (TNF/NF‐κβ, IL6‐STAT3), apoptosis/UPR, cell cycle programs, and glycolysis.
Paulina Werner, Martin Schaier, Gabriel Braun, Anneli Julander, Klara Midander, Marlene Isaksson, Gunda Koellensperger, Lukas Wisgrill, Nanna Fyhrquist   +8 more
wiley   +1 more source