Results 51 to 60 of about 177,513 (261)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Enhanced Blind Interleaver Parameters Estimation Algorithm for Noisy Environment

open access: yesIEEE Access, 2018
This paper proposes a blind interleaver parameters estimation method enhanced by identifying relatively error-less partial symbols among intercepted streams.
Changryoul Choi, Dongweon Yoon
doaj   +1 more source

Blind Relay Network with Viterbi Detection [PDF]

open access: yes2014 IEEE Military Communications Conference, 2014
This paper compares the performance of a blind relay communication system with that of a non-blind relay communication system. For a blind system, a differential space-time block code (DSTBC) or a blind Viterbi detection is used, and for a non-blind system, a space-time block code (STBC) is used. Also, this paper takes another blind detection mechanism,
Shuang Feng   +2 more
openaire   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao   +6 more
wiley   +1 more source

Blind audio watermarking mechanism based on variational Bayesian learning

open access: yesTongxin xuebao, 2015
In order to improve the performance of audio watermarking detection,a blind audio watermarking mechanism using the statistical characteristics based on MFCC features of audio frames was proposed.The spread spectrum watermarking was embedded in the DCT ...
Xin TANG   +3 more
doaj  

Blind sequential detection for sparse ISI channels

open access: yesEURASIP Journal on Advances in Signal Processing, 2018
We present a computationally efficient blind sequential detection method for data transmitted over a sparse intersymbol interference channel. Unlike blind sequential detection methods designed for general channels, the proposed method exploits the ...
Weiwei Zhou, Jill K. Nelson
doaj   +1 more source

[18F]Fluorodeprenyl‐D2 PET as a Tool to Monitor Disease Activity in GAD65‐Ab Autoimmune Encephalitis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate [18F]fluorodeprenyl‐D2 ([18F]F‐DED) positron‐emission tomography (PET) imaging as a biomarker of disease activity in autoimmune encephalitis (AIE) associated with glutamic acid decarboxylase 65 (GAD65) antibodies. Methods [18F]F‐DED PET was performed in 25 GAD65‐AIE patients and 8 controls using dynamic (0–60 min) and ...
Julia S. Dorneich   +19 more
wiley   +1 more source

WPD-based blind image steganalysis

open access: yesTongxin xuebao, 2008
Based on wavelet package decomposition(WPD),a new blind image steganalysis method was presented,which can detect the stego images with comparatively high accuracy.Firstly,by three scales of WPD,image was decomposed into some coefficient subbands,and the ...
LUO Xiang-yang1   +2 more
doaj  

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