Results 241 to 250 of about 2,900,353 (313)

EDNRA Forms a Positive Feedback Loop with the Hippo/YAP Axis to Drive Triple‐Negative Breast Cancer Progression

Advanced Science, EarlyView.
Endothelin receptor type A (EDNRA) and the Hippo/YAP pathway form a self‐reinforcing loop that sustains triple‐negative breast cancer. EDNRA activates YAP through Gαq/11–Rho/ROCK–LATS signaling, while YAP/TEAD4 reciprocally drives EDNRA transcription.
Zehao Hong, Boyang Li, Jiahui Xu, Ruonan Lin, Jinghao Pan, Chenlu Fang, Boxiang Zhang, Lucy Yue Lau, Richard J. Aldridge, Elizabeth A. Whitmore, Yi Chen   +10 more
wiley   +1 more source

Trusting the Algorithm or Trusting the Nurse? Critical Care Nurses' Experiences of Automation Bias and Professional Autonomy in AI-Assisted Early Warning. [PDF]

Nurs Crit Care
Samy R, Ramadan OME, Elsayed GEA.
europepmc   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Determining the Physiological Threshold for Angina (ORBITA-FIRE): A Double-Blind, Randomized, Placebo-Controlled Study. [PDF]

Circulation
Ahmed-Jushuf F, Foley MJ, Chotai S, Rajkumar CA, Wang D, Simader FA, Macierzanka K, Chiew K, Misra S, Williams R, Konstantinou K, Din JN, Mohdnazri SR, O'Kane PD, Haworth P, Nijjer SS, Seligman H, Keeble TR, Davies JR, Clesham G, Hinton J, Spratt JC, Dungu JN, Knight D, Kotecha T, Harrell FE, Howard JP, Francis DP, Shun-Shin MJ, Al-Lamee RK.   +29 more
europepmc   +1 more source

Patient-Reported Quality of Life and Treatment Experiences Among Patients with Neovascular Age-Related Macular Degeneration Receiving Intravitreal Aflibercept in Colombia: A Qualitative Study. [PDF]

Clin Ophthalmol
Piedrahita MA, Arias-Ortiz WA, Acosta Cadavid CP, Cadena Galvis E, Peña FY.   +4 more
europepmc   +1 more source

Eye movement desensitisation and reprocessing for post-traumatic stress in survivors of critical illness (EMERALD): a mixed-methods, randomised, single-blind, parallel group-controlled, feasibility trial. [PDF]

EClinicalMedicine
Bates A, Cusack R, Golding H, Moyses H, Southam H, Rushbrook S, Highfield J, Pattison N, Baldwin DS, Grocott MPW.   +9 more
europepmc   +1 more source

AVATAR therapy for distressing auditory hallucinations: mediators of change in AVATAR1, a single blind randomised control trial with supportive counselling as active control

Fornells-Ambrojo M, Ster AC, Garety P, Craig TKJ, Huckvale M, Emsley R, Edwards C, Hardy A, Ward T, Rus Calafell M.   +9 more
europepmc   +1 more source