Results 11 to 20 of about 455,319 (289)

Biosynthesis of fatty acids: IV. Studies with inhibitors

open access: yesJournal of Lipid Research, 1963
Tetrolyl-CoA and propiolyl-CoA have been shown to be strong noncompetitive inhibitors of fatty acid synthesis. Acrylyl-CoA and isocrotonyl-CoA also inhibit, but much higher concentrations are required.
Joseph D. Robinson   +2 more
doaj   +1 more source

Klotho prevents transforming growth factor-β2-induced senescent-like morphological changes in the retinal pigment epithelium

open access: yesCell Death and Disease, 2023
Degenerative changes of the retinal pigment epithelium (RPE) triggered by transforming growth factor-β2 (TGF-β2) and oxidative stress play a critical role in the progression of age-related macular degeneration (AMD).
Ha Young Jang   +3 more
doaj   +1 more source

Elimination of avoidable blindness due to cataract: where do we prioritize and how should we monitor this decade? [PDF]

open access: yes, 2012
BACKGROUND: In the final push toward the elimination of avoidable blindness, cataract occupies a position of eminence for the success of the Right to Sight initiative. AIMS: Review existing situation and assess what monitoring indicators may be useful to
John, Neena   +3 more
core   +2 more sources

The roles of sex and gender in women’s eye health disparities in the United States

open access: yesBiology of Sex Differences, 2021
Background In the United States, women are at a higher risk of developing vision impairment or a serious eye disease (such as age-related macular degeneration, thyroid eye disease, or chronic dry eye disease) than men.
Irene O. Aninye   +8 more
doaj   +1 more source

Ferulic acid attenuates high glucose-induced apoptosis in retinal pigment epithelium cells and protects retina in db/db mice [PDF]

open access: yesPeerJ, 2022
Background Herein, we aimed to present evidence that Ferulic acid (FA), a phenolic acid, can alleviate high glucose (HG)-induced retinal pigment epithelium (RPE) cell apoptosis and protect retina in db/db mice.
Dejun Zhu   +8 more
doaj   +2 more sources

Using Stem Cells to Model Diseases of the Outer Retina

open access: yesComputational and Structural Biotechnology Journal, 2015
Retinal degeneration arises from the loss of photoreceptors or retinal pigment epithelium (RPE). It is one of the leading causes of irreversible blindness worldwide with limited effective treatment options.
Camille Yvon   +6 more
doaj   +1 more source

Vision Rehabilitation in Patients with Age-related Macular Degeneration

open access: yesRehabilitation Process and Outcome, 2014
Background The aim of this study was to investigate the rehabilitative process and visual rehabilitation outcomes in patients with central vision loss due to age-related macular degeneration (AMD).
Filippo M. Amore   +5 more
doaj   +1 more source

Intravitreal Ampicillin Sodium for Antibiotic-Resistant Endophthalmitis: Streptococcus uberis First Human Intraocular Infection Report

open access: yesJournal of Ophthalmology, 2010
Purpose. To describe the clinical characteristics, diagnosis, and treatment with intravitreal ampicillin sodium of a postoperative endophthalmitis case due to Streptococcus uberis; an environmental pathogen commonly seen in mastitis cases of lactating ...
Raul Velez-Montoya   +4 more
doaj   +1 more source

Effects of dietary phytol and phytanic acid in animals

open access: yesJournal of Lipid Research, 1966
Feeding of phytol in large doses (2-5% by weight in the diet) led to accumulation of phytanic acid in the mouse, rat, rabbit, and chinchilla, the degree of accumulation depending upon the level of dietary intake.
Daniel Steinberg   +6 more
doaj   +1 more source

New Interpretation of Galileo\u2019s Arthritis and Blindness [PDF]

open access: yes, 2015
Galileo Galilei (1564-1642) complained of several disorders during his life, the most important of which were chronic arthritic pains and bilateral blindness.
Barbieri, Cesare   +7 more
core   +2 more sources

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