Results 21 to 30 of about 250,538 (263)

Biosynthesis of fatty acids: IV. Studies with inhibitors

open access: yesJournal of Lipid Research, 1963
Tetrolyl-CoA and propiolyl-CoA have been shown to be strong noncompetitive inhibitors of fatty acid synthesis. Acrylyl-CoA and isocrotonyl-CoA also inhibit, but much higher concentrations are required.
Joseph D. Robinson   +2 more
doaj   +1 more source

Klotho prevents transforming growth factor-β2-induced senescent-like morphological changes in the retinal pigment epithelium

open access: yesCell Death and Disease, 2023
Degenerative changes of the retinal pigment epithelium (RPE) triggered by transforming growth factor-β2 (TGF-β2) and oxidative stress play a critical role in the progression of age-related macular degeneration (AMD).
Ha Young Jang   +3 more
doaj   +1 more source

Causes of childhood blindness in the northeastern states of India. [PDF]

open access: yes, 2008
BACKGROUND: The northeastern region (NER) of India is geographically isolated and ethno-culturally different from the rest of the country. There is lacuna regarding the data on causes of blindness and severe visual impairment in children from this region.
Guha, Kamalesh   +6 more
core   +1 more source

Ferulic acid attenuates high glucose-induced apoptosis in retinal pigment epithelium cells and protects retina in db/db mice [PDF]

open access: yesPeerJ, 2022
Background Herein, we aimed to present evidence that Ferulic acid (FA), a phenolic acid, can alleviate high glucose (HG)-induced retinal pigment epithelium (RPE) cell apoptosis and protect retina in db/db mice.
Dejun Zhu   +8 more
doaj   +2 more sources

Affective Possibilities of Everyday Encounters with Blindness [PDF]

open access: yes, 2022
In this chapter, I reflect upon the different ways that blindness is encountered within the context of everyday life. Everyday encounters provide an interesting site of analysis as they shape, and are shaped by, individuals moving together within ...
Burch, Leah
core   +1 more source

Vision Rehabilitation in Patients with Age-related Macular Degeneration

open access: yesRehabilitation Process and Outcome, 2014
Background The aim of this study was to investigate the rehabilitative process and visual rehabilitation outcomes in patients with central vision loss due to age-related macular degeneration (AMD).
Filippo M. Amore   +5 more
doaj   +1 more source

Using Stem Cells to Model Diseases of the Outer Retina

open access: yesComputational and Structural Biotechnology Journal, 2015
Retinal degeneration arises from the loss of photoreceptors or retinal pigment epithelium (RPE). It is one of the leading causes of irreversible blindness worldwide with limited effective treatment options.
Camille Yvon   +6 more
doaj   +1 more source

Intravitreal Ampicillin Sodium for Antibiotic-Resistant Endophthalmitis: Streptococcus uberis First Human Intraocular Infection Report

open access: yesJournal of Ophthalmology, 2010
Purpose. To describe the clinical characteristics, diagnosis, and treatment with intravitreal ampicillin sodium of a postoperative endophthalmitis case due to Streptococcus uberis; an environmental pathogen commonly seen in mastitis cases of lactating ...
Raul Velez-Montoya   +4 more
doaj   +1 more source

The roles of sex and gender in women’s eye health disparities in the United States

open access: yesBiology of Sex Differences, 2021
Background In the United States, women are at a higher risk of developing vision impairment or a serious eye disease (such as age-related macular degeneration, thyroid eye disease, or chronic dry eye disease) than men.
Irene O. Aninye   +8 more
doaj   +1 more source

Blindness and visual impairment due to age-related cataract in sub-Saharan Africa: a systematic review of recent population-based studies. [PDF]

open access: yes, 2013
AIM: We aimed to evaluate age-related cataract as a contributor to blindness and visual impairment (VI) in sub-Saharan Africa (SSA). METHODS: A systematic review of population-based studies published between 2000 and October 2012.
Sherwin, Justin C   +2 more
core   +1 more source

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