Results 11 to 20 of about 176,661 (266)

The blind leading the blind [PDF]

BMJ, 2007
A key feature of the government9s new plan for reforming health care in London is “polyclinics” in which GPs and specialists work side by side. But Iona Heath argues that this will be to the detriment of primary care and that patients with complex needs will lose ...
openaire   +2 more sources

Biosynthesis of fatty acids: IV. Studies with inhibitors

Journal of Lipid Research, 1963
Tetrolyl-CoA and propiolyl-CoA have been shown to be strong noncompetitive inhibitors of fatty acid synthesis. Acrylyl-CoA and isocrotonyl-CoA also inhibit, but much higher concentrations are required.
Joseph D. Robinson, Roscoe O. Brady, Roy M. Bradley   +2 more
doaj   +1 more source

Klotho prevents transforming growth factor-β2-induced senescent-like morphological changes in the retinal pigment epithelium

Cell Death and Disease, 2023
Degenerative changes of the retinal pigment epithelium (RPE) triggered by transforming growth factor-β2 (TGF-β2) and oxidative stress play a critical role in the progression of age-related macular degeneration (AMD).
Ha Young Jang, Soo-Jin Kim, Kyu-Sang Park, Jeong Hun Kim   +3 more
doaj   +1 more source

To blind or not to blind

Journal of Ozone Therapy, 2021
During this COVID-19 pandemic, I was invited to review several papers from well-reputed and high-impact factor journals. Surprisingly, the review of these papers was not blind, allowing me to know the authors and their institutions. Not blinding the reviews allows reviewers to decide whether accept or not the task and can predispose the reviewer's ...
openaire   +1 more source

Using Stem Cells to Model Diseases of the Outer Retina

Computational and Structural Biotechnology Journal, 2015
Retinal degeneration arises from the loss of photoreceptors or retinal pigment epithelium (RPE). It is one of the leading causes of irreversible blindness worldwide with limited effective treatment options.
Camille Yvon, Conor M. Ramsden, Amelia Lane, Michael B. Powner, Lyndon da Cruz, Peter J. Coffey, Amanda-Jayne F. Carr   +6 more
doaj   +1 more source

Ferulic acid attenuates high glucose-induced apoptosis in retinal pigment epithelium cells and protects retina in db/db mice [PDF]

PeerJ, 2022
Background Herein, we aimed to present evidence that Ferulic acid (FA), a phenolic acid, can alleviate high glucose (HG)-induced retinal pigment epithelium (RPE) cell apoptosis and protect retina in db/db mice.
Dejun Zhu, Wenqing Zou, Xiangmei Cao, Weigang Xu, Zhaogang Lu, Yan Zhu, Xiaowen Hu, Jin Hu, Qing Zhu   +8 more
doaj   +2 more sources

Vision Rehabilitation in Patients with Age-related Macular Degeneration

Rehabilitation Process and Outcome, 2014
Background The aim of this study was to investigate the rehabilitative process and visual rehabilitation outcomes in patients with central vision loss due to age-related macular degeneration (AMD).
Filippo M. Amore, Stefania Fortini, Valeria Silvestri, Marco Sulfaro, Alessia Pacifici, Simona Turco   +5 more
doaj   +1 more source

Intravitreal Ampicillin Sodium for Antibiotic-Resistant Endophthalmitis: Streptococcus uberis First Human Intraocular Infection Report

Journal of Ophthalmology, 2010
Purpose. To describe the clinical characteristics, diagnosis, and treatment with intravitreal ampicillin sodium of a postoperative endophthalmitis case due to Streptococcus uberis; an environmental pathogen commonly seen in mastitis cases of lactating ...
Raul Velez-Montoya, Dulce Rascón-Vargas, William F. Mieler, Jans Fromow-Guerra, Virgilio Morales-Cantón   +4 more
doaj   +1 more source

The roles of sex and gender in women’s eye health disparities in the United States

Biology of Sex Differences, 2021
Background In the United States, women are at a higher risk of developing vision impairment or a serious eye disease (such as age-related macular degeneration, thyroid eye disease, or chronic dry eye disease) than men.
Irene O. Aninye, Kathleen Digre, M. Elizabeth Hartnett, Kira Baldonado, Erin M. Shriver, Laura M. Periman, Julie Grutzmacher, Janine A. Clayton, Society for Women’s Health Research Women’s Eye Health Working Group   +8 more
doaj   +1 more source

Effects of dietary phytol and phytanic acid in animals

Journal of Lipid Research, 1966
Feeding of phytol in large doses (2-5% by weight in the diet) led to accumulation of phytanic acid in the mouse, rat, rabbit, and chinchilla, the degree of accumulation depending upon the level of dietary intake.
Daniel Steinberg, Joel Avigan, Charles E. Mize, James H. Baxter, Jan Cammermeyer, Henry M. Fales, Patricia F. Highet   +6 more
doaj   +1 more source