Results 81 to 90 of about 635,878 (335)
Ivermectin for onchocercal eye disease (river blindness).
BACKGROUND: It is believed that ivermectin (a microfilaricide) could prevent blindness due to onchocerciasis. However, when given to everyone in communities where onchocerciasis is common, the effects of ivermectin on lesions affecting the eye are ...
Ejere, Henry OD+3 more
core +1 more source
ABSTRACT Objective Spinal muscular atrophy (SMA) significantly impacts motor function. This study aimed to assess the persistent burden and unmet needs among currently treated patients with SMA and their caregivers. Methods Two complementary web‐based surveys were distributed in August 2024 among patients with SMA and their caregivers.
Julie A. Parsons+8 more
wiley +1 more source
The Resurrection of the Duty to Inquire After Therasense v. Becton, Dickinson & Co. [PDF]
Balancing a duty to a tribunal and a duty to a client can paralyze a lawyer. The task raises difficult questions about how to reconcile competing obligations as an advocate and as an officer of the court.
Woolard, Brandee
core +1 more source
Identification of Dementia With Lewy Bodies by Skin Biopsy in Recent‐Onset Cognitive Impairment
ABSTRACT Immunofluorescence for phosphorylated alpha‐synuclein in skin biopsy samples is an emerging biomarker in synucleinopathies comprising Dementia with Lewy bodies. In this pilot study, 19 patients with recent‐onset (≤ 18 months) cognitive impairment underwent skin biopsy at baseline, with follow‐up clinical re‐evaluation.
Alessandro Furia+13 more
wiley +1 more source
Developing Successful Global Health Alliances [PDF]
Examines the circumstances that call for alliance formation to reduce the burdens of AIDS, tuberculosis, malaria, polio, river blindness, and many other diseases; the utility of various alliance models; and the characteristics of successful ...
core
ABSTRACT Purpose This study aimed to explore the association between quantitative shape irregularity and density heterogeneity of hematomas and hematoma expansion (HE) for intracerebral hemorrhage (ICH) patients. Methods This cohort study included patients arriving within 24 h of symptom onset between August 2021 and July 2022 as the derivation cohort ...
Zeqiang Ji+11 more
wiley +1 more source
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos+17 more
wiley +1 more source
Detection of Hard Exudates in Retinal Fundus Images using Deep Learning
Diabetic Retinopathy (DR) is a retinal disorder that affects the people having diabetes mellitus for a long time (20 years). DR is one of the main reasons for the preventable blindness all over the world. If not detected early the patient may progress to
Benzamin, Avula, Chakraborty, Chandan
core +1 more source
ABSTRACT Objective To identify metabolic patterns in the brain and musculoskeletal system of stiff person syndrome spectrum disorders (SPSD) patients over time using PET imaging and evaluate the impact of immune therapy on metabolic activity as a surrogate for treatment response.
Munther M. Queisi+4 more
wiley +1 more source
Introduction: Pterygium is a common multifactorial external eye disease, which causes various ocular symptoms and negatively affects appearance. The aim of this study was to analyze the epidemiological characteristics and the change of surgical methods ...
Jingyi Wang+8 more
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