Results 71 to 80 of about 41,356 (289)

Deucravacitinib in Active Psoriatic Arthritis: Efficacy and Safety Up to 52 Weeks From the Randomized, Double‐Blind, Phase 3 POETYK PsA‐2 Trial

Arthritis &Rheumatology, EarlyView.
Objective To assess the efficacy and safety of deucravacitinib, an oral, selective tyrosine kinase 2 inhibitor, in patients with psoriatic arthritis (PsA) who were naive to biologic disease‐modifying antirheumatic drugs or received tumor necrosis factor inhibitors. Methods In the 52‐week, double‐blind, placebo‐controlled, phase 3 Program for Evaluation
Philip J. Mease, Vinod Chandran, April W. Armstrong, Ricardo Blanco, Alexis Ogdie, Evan L. Siegel, Alice B. Gottlieb, Xiaofeng Zeng, Diamant Thaçi, Mitsumasa Kishimoto, Hendrik Schulze‐Koops, Alan Kivitz, Eva Dokoupilová, Akimichi Morita, Eric M. Ruderman, Michael Plewinski, Kejia Wang, Caroline Sardinas, Eleni Vritzali, John Vaile, Atul Deodhar   +20 more
wiley   +1 more source

BLISTERING BY SUGGESTION. [PDF]

JAMA: The Journal of the American Medical Association, 1895
As early as 1840 Dr. Lewis Prejalmini with "magnetized" paper produced the effect of cantharides. As Bjornstrom remarks, suggestion not"magnetized" paper caused the blistering. Bjornstrom demonstrates that, by suggestion, congestion may be produced, carried to raised swelling of the skin, to a blister like that of cantharides, to bloody transudation ...
openaire   +2 more sources

Bullous Pemphigoid: A Series Of 50 Cases [PDF]

Geriatrics, Gerontology and Aging
OBJECTIVES: This study aims to analyze data on the epidemiology, treatment and course of bullous pemphigoid in 50 patients and compare findings to the data already available in the literature.
Tatiana Miyuki Iida, Taila Yuri Siqueira Machado, Adriana Maria Porro   +2 more
doaj   +1 more source

Repeated intradermal lipopolysaccharide challenge responses in healthy volunteers: Implications for clinical pharmacology studies

British Journal of Clinical Pharmacology, EarlyView.
Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé, Juliette A. van den Noort, Iva Lelios, Diana R. Pereira, Marzia A. Scelsi, Erica S. Klaassen, Philipp Schoenenberger, Naomi B. Klarenbeek, Pierre‐Eric Juif, Pascal Espie, Manon A. A. Jansen, Matthijs Moerland, Richard W. D. Welford   +12 more
wiley   +1 more source

Lost and found in translation: the value of the human imiquimod model

British Journal of Clinical Pharmacology, EarlyView.
Topical imiquimod (IMQ), a Toll‐like receptor (TLR) 7 agonist, induces transient cutaneous inflammation and is widely used in preclinical research as a ‘psoriasis‐like’ mouse model. However, accumulating evidence indicates substantial divergence between IMQ‐driven biology and human plaque psoriasis pathogenesis.
Anouk C. Meijs, Juliette A. van den Noort, Salma Assil, Naomi B. Klarenbeek, Matthijs Moerland, Tessa Niemeyer‐van der Kolk, Robert Rissmann   +6 more
wiley   +1 more source

Patient preferences for medicines information in cardiovascular disease and the influence of unmet needs on medication adherence: A cross‐sectional study

British Journal of Clinical Pharmacology, EarlyView.
A survey of 313 Australians with cardiovascular disease found strong preferences for digitally delivered medicine information. Half of participants reported unmet information needs related to their medicines, which were associated with lower medication adherence.
Lachlan L. Dalli, Susie Cartledge, Caroline Trin, Zuhayr Alji, Justine Causing, Monique F. Kilkenny, Antonia Arfaras, Stella Talic   +7 more
wiley   +1 more source

Picture of a smart blister pack showing resemblance to regular blister packs.

, 2015
Picture of a smart blister pack showing resemblance to regular blister packs.
S. Patrick Kachur (81465), Katia Bruxvoort (510860), Charles Festo (551562), Catherine Goodman (265714), Frank Mayaya (775897), David Schellenberg (33891), Matthew Cairns (91805), Admirabilis Kalolella (551559)   +7 more
core   +1 more source

Measuring Patient Adherence to Malaria Treatment: A Comparison of Results from Self-Report and a Customised Electronic Monitoring Device.

PLoS ONE, 2015
BackgroundSelf-report is the most common and feasible method for assessing patient adherence to medication, but can be prone to recall bias and social desirability bias.
Katia Bruxvoort, Charles Festo, Matthew Cairns, Admirabilis Kalolella, Frank Mayaya, S Patrick Kachur, David Schellenberg, Catherine Goodman   +7 more
doaj   +1 more source

Caveolin‐1 enriched apoptotic bodies derived from oral hard palate orchestrate bone remodeling to treat heterotopic ossification

BMEMat, EarlyView.
Downregulated CAV1 in HO is restored via apoptotic bodies from PMSCs, which reprogram bone remodeling by delivering CAV1 to target cells, highlighting the therapeutic role of EV subtypes in heterotopic ossification. Abstract Heterotopic ossification (HO) is a pathological process characterized by ectopic bone formation in non‐osseous tissues, with an ...
Yuchen Wang, Like Tang, Zhou Yu, Wenjin Cai, Qifeng Jiang, Zhikang Wang, Yitong Chen, Kaichen Lai, Ying Wang, Tim Forouzanfar, Chiyuan Ma, Gang Wu, Tingben Huang, Guoli Yang   +13 more
wiley   +1 more source

Hijama blister

Indian Dermatology Online Journal, 2023
Karthikeyan, Kaliaperumal, Sadhasivamohan, Anusuya   +1 more
openaire   +2 more sources