Results 41 to 50 of about 241,559 (311)

An Efficient Scheme for Coupling OpenMC and FLUENT with Adaptive Load Balancing

open access: yesScience and Technology of Nuclear Installations, 2021
This paper develops a multi-physics interface code MC-FLUENT to couple the Monte Carlo code OpenMC with the commercial computational fluid dynamics code ANSYS FLUENT.
Qingyang Zhang   +7 more
doaj   +1 more source

Codewords generated by UP-valued functions

open access: yesAIMS Mathematics, 2021
The concept of a UP-valued function on a nonempty set was introduced by Ansari et al. [3]. Codewords in a binary block-code generated by a UP-valued function are established and some interesting results are obtained.
Ronnason Chinram, Aiyared Iampan
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

NOISE IMMUNITY CODES DISPLAY IN RELIABILITY CORDINATES

open access: yesInformation and Telecommunication Sciences, 2015
Background. Noise immunity codes are widely used in the modern telecommunication systems. The methodology of properties count of convolutional codes, offered by authors before, to the equivalent parameters of block codes gave the opportunity to use the ...
Leonid Uryvskyi, Anton Pieshkin
doaj   +1 more source

Space-time block codes versus space-frequency block codes

open access: yesThe 57th IEEE Semiannual Vehicular Technology Conference, 2003. VTC 2003-Spring., 2004
In wireless broadband systems the available time, frequency and spatial diversity can be exploited using complex space-time-frequency codes. However, in order to retain a flexible scheme with low complexity we prefer a concatenated system where a channel code picks up time and frequency diversity and a simple orthogonal design is used to obtain spatial
openaire   +2 more sources

Body composition, energy expenditure, and markers of hemolysis in adults with sickle cell disease

open access: yesNAJFNR, 2022
Background: Historically, malnutrition is described in individuals with SCD. However, more recent studies have shown a change in the profile of the nutritional status and distribution of body composition of SCD patients, mainly adult individuals.
Karen Cordovil   +3 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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