Results 61 to 70 of about 2,917,992 (321)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
AIMS MathematicsThis paper classifies all flag-transitive point-primitive nontrivial $ 2 $-$ (v, k, \lambda) $ designs whose automorphism groups have socle $ A_n $ for $ n = 6, 7, 8 $. Up to isomorphism, there are exactly 50 such designs, including 11 full designs and 3
Delu Tian, Qianfen Liao, Zhilin Zhang
doaj +1 more source
About Some Properties and Constructions of Experimental Designs
Acta Universitatis Lodziensis. Folia Oeconomica, 2016 In this paper, we consider the problems related to the determining plan of the experiment performed according to the model of the chemical balance weighing design under additional assumption that the experimental errors are equally negatively correlated.
Bronisław Ceranka, Małgorzata Graczyk
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
D-Optimal Design for a Causal Structure for Completely Randomized and Random Blocked Experiments [PDF]
, 2022 Zaher Kmail, Kent M. Eskridge
openalex +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
CAFS: A Cesium Atomic Frequency Standard for GPS block IIR [PDF]
Kernco, Inc. was selected to design the Cesium Atomic Frequency Standards (CAFS) for the GPS Block IIR NAVSTAR satellites. These spacecraft are scheduled to be launched in the mid-1990's to replenish and upgrade the existing constellation of Global ...
Wisnia, Jeffry A.
core +1 more source
Coordinated Multicasting with Opportunistic User Selection in Multicell Wireless Systems
, 2015 Physical layer multicasting with opportunistic user selection (OUS) is examined for multicell multi-antenna wireless systems. By adopting a two-layer encoding scheme, a rate-adaptive channel code is applied in each fading block to enable successful ...
Chang, Tsung-Hui +3 more
core +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source