Results 71 to 80 of about 2,940,629 (293)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Construction of Block Design-Based Piggybacking Codes
Based on maximum distance separable (MDS) codes, existing Piggybacking codes can reduce the repair bandwidth overhead of systematic nodes effectively, but there are still challenges such as larger repair degree, higher repair bandwidth of parity nodes ...
LI Tong, WANG Jing, ZHANG Jiewei, YANG Hongzhi, LIU Xiangyang
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Design keystone-shaped concrete block
No ...
S.F.S.
doaj +1 more source
New Results Regarding the Construction Method for D‑optimal Chemical Balance Weighing Designs
We study an experiment in which we determine unknown measurements of p objects in n weighing operations according to the model of the chemical balance weighing design. We determine a design which is D‑optimal. For the construction of the D‑optimal design,
Bronisław Ceranka, Małgorzata Graczyk
doaj +1 more source
Array Convolutional Low-Density Parity-Check Codes
This paper presents a design technique for obtaining regular time-invariant low-density parity-check convolutional (RTI-LDPCC) codes with low complexity and good performance. We start from previous approaches which unwrap a low-density parity-check (LDPC)
Baldi, Marco +2 more
core +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Notes on the Regular E-Optimal Spring Balance Weighing Designs with Correlated Errors
The paper deals with the estimation problem of individual weights of objects in Eoptimal spring balance weighing design. It is assumed that errors are equal correlated.
Bronisław Ceranka +1 more
doaj +1 more source

