Structural Variant benchmarking frameworks: Parameterization, matching logic, and evaluation assumptions presented through HG002 and NA12878. [PDF]
PLoS Comput BiolMaden G, Baysan M, Aydın N.
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Blood biomarkers are increasingly critical for non‐invasive Alzheimer's Disease (AD) diagnostics and research but typically require on‐site processing. Remote point‐of‐care collection methods could enhance biomarker testing in clinical and research settings.
Sara Ho +9 more
wiley +1 more source
Improved chest wall stability during deep-inspiration breath-hold in breast cancer radiotherapy following quality improvement initiatives. [PDF]
Phys Imaging Radiat OncolHøgsbjerg KW +6 more
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Investigation of Complement Activation and Cytokine Signatures in AQP4+ NMOSD, MOGAD, and MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Aquaporin‐4‐IgG seropositive neuromyelitis optica spectrum disorder (AQP4+ NMOSD), myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), and multiple sclerosis (MS) are pathophysiologically distinct neuroinflammatory disorders. Complement activation is a major mechanism of injury in AQP4+ NMOSD, whereas its role in
Angeliki G. Filippatou +23 more
wiley +1 more source
Impact of ultrasound-guided nerve block on postoperative delirium in elderly patients undergoing diabetic foot surgery: a propensity score-matched retrospective study. [PDF]
Front Aging NeurosciWen Z, Zheng J, Huang J, Li J.
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks +8 more
wiley +1 more source
A Two‐Stage Plasma Biomarker Algorithm Reduces Amyloid PET Use and the p‐Tau217 Gray Zone
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma p‐Tau217 leaves 30%–50% of patients in an indeterminate “gray zone” often requiring Aβ‐PET. We developed GRAD (Gatekeeper‐Reflex for Alzheimer's Disease), a two‐stage Aβ‐positivity prediction model to improve classification while reserving Aβ‐PET for residual uncertainty.
Harthik Parankusham +7 more
wiley +1 more source
Independent Associations of Stroke and Sarcopenia-Related Phenotype with Lower-Limb Strength and Gait: A 1:2 Matched Cohort Analysis. [PDF]
J Clin MedShin S, Lee Y.
europepmc +1 more source
Review and optimization of image classification models for edge AI applications. [PDF]
Nano ConvergKim S, Cho H, Kim T, Lee H, An S, Ryu S.
europepmc +1 more source