Results 61 to 70 of about 731,157 (280)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Block-Matching Optical Flow for Dynamic Vision Sensor- Algorithm and FPGA Implementation

open access: yes, 2017
Rapid and low power computation of optical flow (OF) is potentially useful in robotics. The dynamic vision sensor (DVS) event camera produces quick and sparse output, and has high dynamic range, but conventional OF algorithms are frame-based and cannot ...
Delbruck, Tobi, Liu, Min
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

CDP-MVS: Forest Multi-View Reconstruction with Enhanced Confidence-Guided Dynamic Domain Propagation

open access: yesRemote Sensing
Using multi-view images of forest plots to reconstruct dense point clouds and extract individual tree parameters enables rapid, high-precision, and cost-effective forest plot surveys.
Zitian Liu   +3 more
doaj   +1 more source

A Coarse-to-Fine Geometric Scale-Invariant Feature Transform for Large Size High Resolution Satellite Image Registration

open access: yesSensors, 2018
Large size high resolution (HR) satellite image matching is a challenging task due to local distortion, repetitive structures, intensity changes and low efficiency.
Xueli Chang   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Matched bipartite block model with covariates

open access: yes, 2017
Community detection or clustering is a fundamental task in the analysis of network data. Many real networks have a bipartite structure which makes community detection challenging. In this paper, we consider a model which allows for matched communities in the bipartite setting, in addition to node covariates with information about the matching.
Razaee, Zahra S   +2 more
openaire   +4 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Optimal Design of Intergovernmental Grants under Asymmetric Information [PDF]

open access: yes, 2003
This paper develops a theoretical explanation why it may be optimal for higher-level governments to pay categorical block grants or closed-ended matching grants to local governments.
Huber, Bernd, Runkel, Marco
core  

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