Results 81 to 90 of about 731,157 (280)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Block matching low-rank for ghost imaging
Optics Express, 2019 High-quality ghost imaging (GI) under low sampling is very important for scientific research and practical application. How to reconstruct high-quality image from low sampling has always been the focus of ghost imaging research. In this work, based on the hypothesis that the matrix stacked by the vectors of image's nonlocal similar patches is of low ...
Heyan Huang +3 more
openaire +2 more sources
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Fast motion estimation based on the special and temporal characteristic
Tongxin xuebao, 2013 The spacial and temporal character of motion vector were analysed according to the spacial and temporal characteristic of motion vector,the different proposed search schemes were adopted for motion estimation;The experimental results shows the proposed ...
Long LIU +3 more
doaj
Supporting Work for Low-Income People With Significant Challenges Summary [PDF]
, 2008 Welfare programs require people to work, but some low-income adults struggle with major personal challenges that make it hard to find or hold down a job.
Karin Martinson, Pamela Loprest
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Image denoising in acoustic microscopy using block-matching and 4D filter. [PDF]
Sci Rep, 2023 Gupta SK +4 more
europepmc +1 more source
Insights on Variance Estimation for Blocked and Matched Pairs Designs
, 2020 Evaluating blocked randomized experiments from a potential outcomes perspective has two primary branches of work. The first focuses on larger blocks, with multiple treatment and control units in each block.
Miratrix, Luke W., Pashley, Nicole E.
core
Many Access for Small Packets Based on Precoding and Sparsity-aware Recovery [PDF]
, 2016 Modern mobile terminals produce massive small data packets. For these short-length packets, it is inefficient to follow the current multiple access schemes to allocate transmission resources due to heavy signaling overhead.
Chen, Xiaohui +4 more
core +3 more sources