Results 131 to 140 of about 3,133,998 (302)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Approximate Schur Complement Preconditioners for Half-Quadratic Image Restoration With Zero Boundary Conditions

Journal of Mathematics
In this paper, the additive half-quadratic image restoration problem with zero boundary conditions is investigated. The Newton method is used to solve this problem and a structured linear system needs solving at each step.
Chaojie Wang, Shuen Sun, Jie Chen, Biling Liu   +3 more
doaj   +1 more source

Change of basis for tridiagonal pairs of type II

Nuclear Physics B
This paper is on the topic of tridiagonal pairs of type II. These involve two linear transformations A and A⋆. We define two bases. In the first one, A acts as a diagonal matrix while A⋆ acts as a block tridiagonal matrix, and in the second one, A acts ...
Nicolas Crampé, Julien Gaboriaud, Satoshi Tsujimoto   +2 more
doaj   +1 more source

Block distance matrices [PDF]

, 2004
In this paper, block distance matrices are introduced. Suppose F is a square block matrix in which each block is a symmetric matrix of some given order. If F is positive semidefinite, the block distance matrix D is defined as a matrix whose (i, j)-block ...
Balaji, R., Bapat, R. B.
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A unifying framework for higher order derivatives of matrix functions

We present theory for general partial derivatives of matrix functions of the form f(A(x)) where A(x) is a matrix path of several variables (x=(x1,...,xj)). Building on results by Mathias [SIAM J. Matrix Anal. Appl., 17 (1996), pp.
Rubensson, Emanuel H.,
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

An Improved Block Diagonalization Precoding Algorithm

工程科学与技术, 2018
In order to improve the performance of block diagonalization precoding algorithm,an improved algorithm was proposed for multiuser multiple-input multiple-output (MIMO) downlink systems,which employs QR decomposition based on Givens transformation.In the ...
Ming GAO, Chengyue SUN, Shaoxing LIN, Yong WANG   +3 more
doaj