Results 121 to 130 of about 1,500,614 (287)
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Block covariance matrix estimation with structured off-diagonal blocks
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Monika Mokrzycka, Malwina Mrowińska
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Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
The mechanical behavior of block-in-matrix materials is heavily dependent on their block content. This parameter is in most cases obtained through visual analyses of the ground through digital imagery, which provides the areal block proportion (ABP) of ...
Andrés Cristóbal +7 more
doaj +1 more source
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
In this paper, the additive half-quadratic image restoration problem with zero boundary conditions is investigated. The Newton method is used to solve this problem and a structured linear system needs solving at each step.
Chaojie Wang +3 more
doaj +1 more source
Change of basis for tridiagonal pairs of type II
This paper is on the topic of tridiagonal pairs of type II. These involve two linear transformations A and A⋆. We define two bases. In the first one, A acts as a diagonal matrix while A⋆ acts as a block tridiagonal matrix, and in the second one, A acts ...
Nicolas Crampé +2 more
doaj +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Block incomplete factorization preconditioners for a symmetric block-tridiagonal M-matrix
New block incomplete factorization preconditioners are introduced for a symmetric block-tridiagonal \(M\)-matrix. Parallel computations and the main properties including spectral properties of the method are analysed.
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