Results 101 to 110 of about 2,984,671 (302)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
LSB-based pre-embedding video steganography with rotating & shifting poly-pattern block matrix. [PDF]
PeerJ Comput Sci, 2022 Hacimurtazaoglu M, Tutuncu K.
europepmc +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Efficient Block Approximate Matrix Multiplication.
, 2023 Randomized matrix algorithms have had significant recent impact on numerical linear algebra. One especially powerful class of methods are algorithms for approximate matrix multiplication based on sampling. Such methods typically sample individual matrix rows and columns using carefully chosen importance sampling probabilities. However, due to practical
Yang, Chuhan, Musco, Christopher
openaire +3 more sources
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Journal of Harbin University of Science and Technology, 2019 In order to solve the problem of whether the matrices generated by two unipotent matrices are unipotency, a new combinatorial property of generators of free groups is obtained by using the matrix logarithmic tool。From the point of the combination of ...
YANG Xin-song, MA Chang
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Parallel sparse matrix solution for direct circuit simulation on a multiple FPGA system [PDF]
, 2012 SPICE, from the University of California, at Berkeley, is the de facto world standard for circuit simulation. SPICE is used to model the behaviour of electronic circuits prior to manufacturing to decrease defects and hence reduce costs. However, accurate
Nechma, Tarek
core +1 more source
Zhejiang Daxue xuebao. Lixue ban, 2018 Based on the existing algorithms,we further study relaxed modulus-based synchronous block multisplitting multi-parameters methods for linear complementarity problem. Furthermore, we give the weaker convergence results of our new method in this paper when
ZHANGLitao(张理涛) +2 more
doaj +1 more source