Results 81 to 90 of about 425,063 (266)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
LSB-based pre-embedding video steganography with rotating & shifting poly-pattern block matrix. [PDF]
PeerJ Comput Sci, 2022 Hacimurtazaoglu M, Tutuncu K.
europepmc +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Journal of Harbin University of Science and Technology, 2019 In order to solve the problem of whether the matrices generated by two unipotent matrices are unipotency, a new combinatorial property of generators of free groups is obtained by using the matrix logarithmic tool。From the point of the combination of ...
YANG Xin-song, MA Chang
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
, 2018 In this paper the idea t of vague matrix is extended in the field of vague block matrix and discussed some of their relational operations on vague block matrices.
openaire +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Zhejiang Daxue xuebao. Lixue ban, 2018 Based on the existing algorithms,we further study relaxed modulus-based synchronous block multisplitting multi-parameters methods for linear complementarity problem. Furthermore, we give the weaker convergence results of our new method in this paper when
ZHANGLitao(张理涛) +2 more
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Consistent Block Diagonal and Exclusive Multi-view Subspace Clustering [PDF]
Jisuanji kexueSubspace clustering method provides an effective solution to the clustering problem of high-dimensional multi-view data.Focusing on the issue that the representation matrix cannot obey the block diagonal property directly by using low rank or sparse ...
WU Jie, WAN Yuan, LIU Qiujie
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source