Results 71 to 80 of about 5,909,835 (371)
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
We first give the block style spectral decomposition of arbitrary block skew circulant matrix with skew circulant blocks. Secondly, we obtain the singular value of block skew circulant matrix with skew circulant blocks as well.
Zhaolin Jiang, Juan Li, Jianwei Zhou
doaj +1 more source
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
On the Cartan matrix of Mackey algebras [PDF]
Let k be a field of characteristic p>0, and G be a finite group. The first result of this paper is an explicit formula for the determinant of the Cartan matrix of the Mackey algebra mu_k(G) of G over k.
Bouc, Serge
core +1 more source
Fast Hessenberg reduction of some rank structured matrices
We develop two fast algorithms for Hessenberg reduction of a structured matrix $A = D + UV^H$ where $D$ is a real or unitary $n \times n$ diagonal matrix and $U, V \in\mathbb{C}^{n \times k}$.
Gemignani, Luca, Robol, Leonardo
core +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Strong Laws for Urn Models with Balanced Replacement Matrices
We consider an urn model, whose replacement matrix has all entries nonnegative and is balanced, that is, has constant row sums. We obtain the rates of the counts of balls corresponding to each color for the strong laws to hold.
Dasgupta, Amites, Maulik, Krishanu
core +1 more source
The block-diagonal least squares method, which theoretically has specific requirements for the observation data and the spatial distribution of its precision, plays an important role in ultra-high degree gravity field determination. On the basis of block-
Wei Liang +3 more
doaj +1 more source
Deficiency indices of block Jacobi matrices and Miura transformation
We study the infinite Jacobi block matrices under the discrete Miura-type transformations which relate matrix Volterra and Toda lattice systems to each other and the situations when the deficiency indices of the corresponding operators are the same.
Osipov Andrey
doaj +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source

