Results 71 to 80 of about 5,896,098 (374)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Abstract and Applied Analysis, 2014 We first give the block style spectral decomposition of arbitrary block skew circulant matrix with skew circulant blocks. Secondly, we obtain the singular value of block skew circulant matrix with skew circulant blocks as well.
Zhaolin Jiang, Juan Li, Jianwei Zhou
doaj +1 more source
Entanglement and Density Matrix of a Block of Spins in AKLT Model
, 2008 We study a 1-dimensional AKLT spin chain, consisting of spins $S$ in the bulk and $S/2$ at both ends. The unique ground state of this AKLT model is described by the Valence-Bond-Solid (VBS) state.
A. Affleck +68 more
core +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Deficiency indices of block Jacobi matrices and Miura transformation
Special Matrices, 2022 We study the infinite Jacobi block matrices under the discrete Miura-type transformations which relate matrix Volterra and Toda lattice systems to each other and the situations when the deficiency indices of the corresponding operators are the same.
Osipov Andrey
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Latent Multi-View Semi-Nonnegative Matrix Factorization with Block Diagonal Constraint
Axioms, 2022 Multi-view clustering algorithms based on matrix factorization have gained enormous development in recent years. Although these algorithms have gained impressive results, they typically neglect the spatial structures that the latent data representation ...
Lin Yuan +3 more
doaj +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
A Note on the Eigenvalue Analysis of the SIMPLE Preconditioning for Incompressible Flow
Journal of Applied Mathematics, 2012 We consider the SIMPLE preconditioning for block two-by-two generalized saddle point problems; this is the general nonsymmetric, nonsingular case where the (1,2) block needs not to equal the transposed (2,1) block, and the (2,2) block may not be zero ...
Shi-Liang Wu, Feng Chen, Xiao-Qi Niu
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Geodesy and Geodynamics, 2016 The block-diagonal least squares method, which theoretically has specific requirements for the observation data and the spatial distribution of its precision, plays an important role in ultra-high degree gravity field determination. On the basis of block-
Wei Liang +3 more
doaj +1 more source