Results 121 to 130 of about 4,791 (236)

Endothelial Integrin‐Linked Kinase (ILK) Deficiency Promotes Endothelial Activation and Cardiovascular Dysfunction via Receptor Interacting Protein Kinase‐1 (RIPK1) Enriched‐Extracellular Vesicle Signalling

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
Endothelial ILK loss drives RIPK1‐enriched EVs that propagate systemic endothelial activation and cardiovascular remodelling. EV cargo remodelling induces early endothelial injury, microvascular dysfunction and chronic cardiac alterations through a RIPK1 dependent pathway.
Alberto Cook‐Calvete   +9 more
wiley   +1 more source

A katE katG double-knockout E. coli strain eliminates the risk of catalase contamination in recombinant proteins. [PDF]

open access: yesAppl Microbiol Biotechnol
Scholz AT   +12 more
europepmc   +1 more source

Stage‐Specific Molecular Cargo of Schwann Cell–Derived Extracellular Vesicles is Associated With Peripheral Nerve Repair

open access: yesJournal of Extracellular Biology, Volume 5, Issue 6, June 2026.
ABSTRACT Schwann cells (SCs) play a critical role in peripheral nerve regeneration, undergoing dynamic phenotype transitions from myelinating to repair stages following injury. While SC‐derived extracellular vesicles (SC‐EVs) have emerged as key mediators of intercellular communication during nerve repair, their stage‐specific molecular cargo and ...
Manju Sharma   +4 more
wiley   +1 more source

An Examination of Task‐Evoked fMRI Data Processing in Functional Connectivity

open access: yesJournal of Neuroscience Research, Volume 104, Issue 6, June 2026.
In this work, we analyzed the preprocessing of task‐fMRI data to explore the contribution of the task information in connectomics towards a methodological consensus for preprocessing among task‐state connectivity studies. We investigated whether a task‐free connectivity can be inferred from task‐fMRI and examined its impact upon a clinical disorder ...
Alice Giubergia   +8 more
wiley   +1 more source

Pre‐Conditioned Bone Marrow Mesenchymal Stromal Cell‐Derived Secretome Exerts an Anti‐Inflammatory Effect on Degenerative Nucleus Pulposus Cells In Vitro

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
IL‐1β‐preconditioned BM‐MSC‐derived secretome counteracts inflammation‐driven degeneration in hNPCs. BM‐MSCs were preconditioned with IL‐1β (10 ng/mL) for 24 h, and the resulting secretome (BM‐MSCsec) was collected. Degenerative hNPCs cultured in a 3D alginate bead model were exposed to IL‐1β to reproduce an inflammatory degenerative microenvironment ...
Veronica Tilotta   +7 more
wiley   +1 more source

Acetate‐Linked Energy Metabolism as a Determinant of Early Haemophilus influenzae Infection Fitness

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
The Pta–AckA pathway is critical for Haemophilus influenzae energy generation, metabolic homeostasis, stress resistance, and intracellular colonization, highlighting its potential as a target for management of H. influenzae infections.
Marufa Nasreen   +8 more
wiley   +1 more source

Feedback-integrated prompt optimiser for problem formulation. [PDF]

open access: yesSci Rep
Amarasinghe PT   +3 more
europepmc   +1 more source

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