Results 161 to 170 of about 2,559,254 (252)

Cache-efficient and vectorized parallel dynamic programming for RNA folding. [PDF]

PLoS One
Gruzewski M, Palkowski M.
europepmc   +1 more source

Comparing the Performance of Double‐Stranded and Single‐Stranded DNA Libraries for Ancient Oral Microbiome Reconstruction

Molecular Ecology Resources, Volume 26, Issue 7, October 2026.
ABSTRACT DNA library construction methods can affect the recovery of ancient DNA, thus influencing downstream analyses. While single‐stranded library preparation (ssLib) has been shown to outperform double‐stranded (dsLib) for highly degraded vertebrate host DNA, especially for samples older than 40,000 years, few studies have examined how library ...
Keri Burge, Irina M. Velsko, Domingo C. Salazar‐García, María Haber Uriarte, Joaquín Lomba Maurandi, Christina Warinner   +5 more
wiley   +1 more source

A katE katG double-knockout E. coli strain eliminates the risk of catalase contamination in recombinant proteins. [PDF]

Appl Microbiol Biotechnol
Scholz AT, Coppo L, Nolan E, Hernandez M, Wang X, Mishra P, Schnell R, Pató ZA, Chen Y, Dagnell M, Andor A, Cheng Q, Arnér ESJ.   +12 more
europepmc   +1 more source

Inhibiting Glutaminase Reverses Senescence‐Associated Mitochondrial Dysfunction and Skeletal Muscle Decline

Aging Cell, Volume 25, Issue 10, October 2026.
Pharmacological inhibition of glutaminase with drug CB‐839 restores mitochondrial function in senescent myoblasts and enhances muscle strength and endurance in progeria mice. ABSTRACT Age‐associated loss of skeletal muscle mass and function, also known as sarcopenia, is closely linked to mitochondrial dysfunction.
Hamsa Vardini Senthil Kumar, Debanik Choudhury, Pedro Lei, Pihu Mehrotra, Shahryar Shahini, Sydney Swedick, John Toftegaard, Stelios T. Andreadis   +7 more
wiley   +1 more source

Shaping inter-brain plasticity: A feasibility study of enhancing inter-brain synchrony with dyadic neurofeedback. [PDF]

iScience
Francis M, Markus A, Stuhr-Wulff F, Shamay-Tsoory S.   +3 more
europepmc   +1 more source

uPAR‐Targeting T Cell Engager Exerts Senolytic Effects in Mice and Non‐Human Primates With Serum Aminotransferase Activity as a Safety Monitor

Aging Cell, Volume 25, Issue 10, October 2026.
GFD‐CD3, a uPAR‐targeting T‐cell engager, effectively cleared senescent cells and mitigated age‐related pathologies with a favorable safety profile under transaminase‐guided monitoring. ABSTRACT Senolytic CAR‐T cells targeting uPAR induce dose‐dependent toxicities.
Jian Deng, Xiaozhu Zeng, Jing Guo, Lihong Li, Shirui Zou, Nan Liu, Shuai He, Lanzhen Yan, Qiong Wang, Yongjie Zhu, Ben Wang, Dong Yang, Longbao Lv, Xudong Zhao   +13 more
wiley   +1 more source

Protocol to study inflammasome activation in induced pluripotent stem cell-derived macrophages. [PDF]

STAR Protoc
McKee CM, Cranston M, McKay EC, Arefian M, Collins BC, Coll RC.   +5 more
europepmc   +1 more source

An Acidic Tubulointerstitial Microenvironment Delays Cell‐Cycle Progression in Proximal Tubule Cells and Fibroblasts and Synergizes With Lactate to Drive Phenotypic Alterations

Acta Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Background Chronic kidney disease (CKD) is characterized by progressive tubulointerstitial inflammation and fibrosis, particularly affecting the proximal tubule. Both proximal tubular epithelial cells and interstitial fibroblasts contribute to CKD progression through cell‐cycle arrest and phenotypic transitions.
Marie‐Christin Schulz, Virginie Dubourg, Lea Schaude, Natalie Schröder, Eva Janßen, Isabelle Görlich, Stefanie Ruhs, Michael Kopf, Michael Gekle   +8 more
wiley   +1 more source

Digital Twin-Enabled Waveform Optimization for VHF Radio Communication Systems. [PDF]

Sensors (Basel)
Zhong C, Liu B, Zhu W, Wang B, Tan Y, Wang X.   +5 more
europepmc   +1 more source

Inducible tomato defences persist in detached leaves, despite differential plant variety and gene‐dependent expression

Ecological Entomology, Volume 51, Issue 5, Page 866-874, October 2026.
Short‐ and long‐term expression of PPO‐D, PI‐IIc and PR‐1a were assessed in intact plants and detached tomato leaves of two varieties infested with Tetranhycus urticae. Tomato defences were induced in both intact and detached leaves, but the induction levels varied with plant variety and gene assessed.
Mariya Kozak, Diogo P. Godinho, Eren Yayla, Juan Adánez, Inês Fragata, Sara Magalhães, Leonor R. Rodrigues   +6 more
wiley   +1 more source