Results 51 to 60 of about 324,143 (269)

Conducting Polymer Microelectrode Arrays for Simultaneous Electrophysiology and Advanced Brain Imaging

Advanced Functional Materials, EarlyView.
A flexible micro‐electrocorticography array with PEDOT:SS electrodes is shown to be compatible with ultra‐high magnetic field MRI up to 9.4 T. Multimodal brain monitoring is demonstrated by performing simultaneous blood oxygen level‐dependent functional MRI in parallel with electrophysiology.
Sagnik Middya, Alejandro Carnicer‐Lombarte, Stephen Sawiak, Sam Hilton, Vincenzo F Curto, Damiano G Barone, Gabriele S Kaminski Schierle, George G Malliaras   +7 more
wiley   +1 more source

Porous Silicon Nanoneedles Efficiently Deliver Adenine Base Editor to Correct a Recurrent Pathogenic COL7A1 Variant in Recessive Dystrophic Epidermolysis Bullosa

Advanced Materials, EarlyView.
Base editing using nanoneedles efficiently corrects pathogenic variants in the type VII collagen gene of primary fibroblasts from patients with recessive dystrophic epidermolysis bullosa. Nanoneedle editing induces minimal and reversible transcriptional perturbations while restoring the production and secretion of functional type VII collagen.
Salman Ahmad Mustfa, Marija Dimitrievska, Cong Wang, Chenlei Gu, Ningjia Sun, Katarzyna Romańczuk, Pawel Karpinski, Łukasz Łaczmański, John A. McGrath, Joanna Jacków‐Malinowska, Ciro Chiappini   +10 more
wiley   +1 more source

Reliability Level List Based Iterative SISO Decoding Algorithm for Block Turbo Codes [PDF]

, 2018
An iterative Reliability Level List (RLL) based soft-input soft-output (SISO) decoding algorithm has been proposed for Block Turbo Codes (BTCs). The algorithm ingeniously adapts the RLL based decoding algorithm for the constituent block codes, which is a
Sudharsan, V, Vijay Karthik, V, Yamuna, B   +2 more
core   +2 more sources

Artesunate Inhibits Neointimal Hyperplasia by Promoting IRF4 Associated Macrophage Polarization

Advanced Science, EarlyView.
This study shows that macrophage interferon regulatory factor 4 (IRF4) improved arterial injury‐induced neointimal hyperplasia by promoting of M2 polarization via up‐regulating krüppel‐like factor 4 (KLF4) in rodent and nonhuman primate models. Notably, artesunate is identified as a potent inducer of IRF4 in macrophages, and proposed as a promising ...
Jinlin Miao, Yule Yong, Zhaohui Zheng, Kui Zhang, Wei Li, Jiayi Liu, Siyi Zhou, Juan‐juan Qin, Haoyang Sun, Yatao Wang, Xianghui Fu, Xing Luo, Siyu Chen, Zhi‐Gang She, Jingjing Cai, Ping Zhu   +15 more
wiley   +1 more source

On the Performance of Turbo Codes in Quasi-Static Fading Channels [PDF]

, 2005
In this paper, we investigate in detail the performance of turbo codes in quasi-static fading channels both with and without antenna diversity. First, we develop a simple and accurate analytic technique to evaluate the performance of turbo codes in quasi-static fading channels.
arxiv   +1 more source

The Novel Dual GIP and GLP‐1 Receptor Agonist Tirzepatide Attenuates Colon Cancer Development by Regulating Glucose Metabolism

Advanced Science, EarlyView.
Tirzepatide, a dual GIP/GLP‐1 receptor agonist for diabetes, suppresses colorectal cancer growth by targeting glucose metabolism. It inhibits cancer cell proliferation, promotes apoptosis, and induces tumor regression. It reduces glucose uptake and destabilizes HIF‐1α for degradation to downregulate PFKFB3/PFK‐1 enzymes, thus contributing to the ...
Yikai Zhang, Yi Xie, Shenglong Xia, Xinnuo Ge, Jiaying Li, Fang Liu, Fan Jia, Shengyao Wang, Qiao Zhou, Menghan Gao, Weihuan Fang, Chao Zheng   +11 more
wiley   +1 more source

Turbo code design for short blocks

Advanced Satellite Multimedia Systems Conference / Signal Processing for Space Communications Workshop, 2016
This work considers the design of short parallel turbo codes (PTCs) with block lengths in the order of (a few) hundred code bits. In particular we aim at designing codes with large minimum distance.
Thomas Jerkovits, B. Matuz
semanticscholar   +1 more source

The Type III Secretion System (T3SS) of Escherichia Coli Promotes Atherosclerosis in Type 2 Diabetes Mellitus

Advanced Science, EarlyView.
Large‐scale studies indicate a strong relationship between the gut microbiome, type 2 diabetes mellitus (T2DM), and atherosclerotic cardiovascular disease (ASCVD). Here, a higher abundance of the type III secretion system (T3SS) virulence factors of Enterobacteriaceae/Escherichia‐Shigella in patients with T2DM‐related‐ASCVD, which correlates with their
Yao‐Yuan Zhang, Song‐Tao Chen, Gang Chen, Le Zhou, Guo‐Liang Zhou, Xin‐Yuan Yu, Long Yuan, Wei‐Qian Deng, Zhen‐Bo Wang, Jing Li, Yi‐Fu Tu, Da‐Wei Zhang, Yuan li, Abdul Sammad, Xiao Zhu, Kai Yin   +15 more
wiley   +1 more source

Mutant SOD1 aggregates formed in vitro and in cultured cells are polymorphic and differ from those arising in the CNS

Journal of Neurochemistry, Volume 164, Issue 1, Page 77-93, January 2023., 2023
In this issue Nordström et al. show that ALS associated superoxide dismutase 1 (SOD1) aggregates generated in vitro and in cell culture models are deviant from the aggregations that arise in the CNS of Tg mouse models of ALS. The study suggests that development of different strains of SOD1 aggregation in the CNS may depend on different disease ...
Ulrika Nordström, Lisa Lang, Elaheh Ekhtiari Bidhendi, Per Zetterström, Mikael Oliveberg, Jens Danielsson, Peter M. Andersen, Stefan L. Marklund   +7 more
wiley   +1 more source

Turbo Codes Based on Time-Variant Memory-1 Convolutional Codes over Fq [PDF]

, 2011
Two classes of turbo codes over high-order finite fields are introduced. The codes are derived from a particular protograph sub-ensemble of the (dv=2,dc=3) low-density parity-check code ensemble. A first construction is derived as a parallel concatenation of two non-binary, time-variant accumulators.
arxiv   +1 more source