Results 131 to 140 of about 1,026,952 (386)
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source
STUDIES ON AUTONOMIC BLOCKADE. II. OBSERVATIONS ON THE NATURE OF BLOOD PRESSURE FALL WITH HIGH SELECTIVE SPINAL ANESTHESIA IN PREGNANT WOMEN 1 [PDF]
N.S. Assali, Harry Prystowsky
openalex +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
SEQUENTIAL BLOCKADE IN ADENINE BIOSYNTHESIS BY GENETIC LOSS OF AN APPARENT BIFUNCTIONAL DEACYLASE [PDF]
Joseph S. Gots, Edith Gollub
openalex +1 more source
The recent successes of immunotherapy have shifted the paradigm in cancer treatment, but because only a percentage of patients are responsive to immunotherapy, it is imperative to identify factors impacting outcome.
Ziming Wang+32 more
semanticscholar +1 more source
Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli+10 more
wiley +1 more source
PD-1+ regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
Significance PD-1 blockade is a cancer immunotherapy effective in various types of cancer. However, we observed rapid cancer progression, called hyperprogressive disease (HPD), in ∼10% of advanced gastric cancer patients treated with anti–PD-1 monoclonal
Takahiro Kamada+15 more
semanticscholar +1 more source
Quantum Antidots: Coulomb Blockade or no Coulomb Blockade?
Comment on M. Kataoka et al., Phys. Rev. Lett. 83, 160 (1999).
openaire +2 more sources