Results 231 to 240 of about 857,044 (346)

Reviewer #1 (Public review): Concerted changes in the pediatric single-cell intestinal ecosystem before and after anti-TNF blockade

Hengqi Betty Zheng, Benjamin A Doran, Kyle Kimler, Alison Yu, Victor Tkachev, Veronika Niederlova, Kayla Cribbin, Ryan Fleming, Brandi Bratrude, Kayla Betz, Lorenzo Cagnin, Connor McGuckin, Paula Keskula, Alexandre Albanese, Maria Sacta, Joshua de Sousa Casal, Ruben van Esch, Andrew C Kwong, Conner Kummerlowe, Faith Taliaferro, Nathalie Fiaschi, Baijun Kou, Sandra Coetzee, Sumreen Jalal, Yoko Yabe, Michael Dobosz, Matthew F Wipperman, Sara Hamon, George D Kalliolias, Andrea Hooper, Wei Keat Lim, Sokol Haxhinasto, Yi Wei, Madeline Ford, Lusine Ambartsumyan, David L Suskind, Dale Lee, Gail Deutsch, Xuemei Deng, Lauren V Collen, Vanessa Mitsialis, Scott B Snapper, Ghassan Wahbeh, Alex K Shalek, Jose Ordovas-Montanes, Leslie S Kean   +45 more
openalex   +1 more source

INTERCOSTAL NERVE BLOCKADE

, 1986
Klaus Kirnö, Kathleen O. Lindell
openalex   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

Molecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti, Giovanni Germano, Pietro Paolo Vitiello, Alberto Bardelli   +3 more
wiley   +1 more source

LEAP-008: pembrolizumab plus lenvatinib after immunotherapy in non-small cell lung cancer. [PDF]

J Thorac Dis
Fukuda K.
europepmc   +1 more source

Errors occurring while performing neuroaxial blockades. The analysis of clinical cases

, 2017
Vladislav G. Krasnov
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Cardiac Sympathetic Innervation and Ventricular Arrhythmias in Structural Heart Disease: Current Peripheral Neuromodulation Therapies and Emerging Therapeutic Targets. [PDF]

Arrhythm Electrophysiol Rev
Benabou L, Vaseghi M.
europepmc   +1 more source

Attenuation of Cardiovascular Responses Following Spinal Blockade in Patients Treated with Propranolol

, 1983
Oscar J. Viegas, Ram S. Ravindran, Bradley J. Strausburg   +2 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

<p>Converting 'cold' to 'hot' hepatocellular carcinoma for improved immunotherapy (Review)</p>. [PDF]

Mol Med Rep
Hsieh CH, Chuang PC.
europepmc   +1 more source