Results 101 to 110 of about 451,265 (323)
Metastable states of the Ising chain with Kawasaki dynamics
, 2002 We consider a ferromagnetic Ising chain evolving under Kawasaki dynamics at zero temperature. We investigate the statistics of the metastable configurations in which the system gets blocked (statistics of energy, spin correlations, distribution of domain
De Smedt, G., Godreche, C., Luck, J. M.
core +2 more sources
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
Multidimensional item response theory and the force and motion conceptual evaluation
Physical Review Physics Education Research, 2019 Many studies have examined the structure and properties of the Force Concept Inventory (FCI); however, far less research has investigated the Force and Motion Conceptual Evaluation (FMCE).
Jie Yang, Cabot Zabriskie, John Stewart
doaj +1 more source
Molecular Oncology, EarlyView.RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha +10 more
wiley +1 more source
Quantitative Analysis of Axonal Branch Dynamics in the Developing Nervous System.
PLoS Computational Biology, 2016 Branching is an important mechanism by which axons navigate to their targets during neural development. For instance, in the developing zebrafish retinotectal system, selective branching plays a critical role during both initial pathfinding and ...
Kelsey Chalmers +3 more
doaj +1 more source
Statistical cryptanalysis of block ciphers
, 2005 Since the development of cryptology in the industrial and academic worlds in the seventies, public knowledge and expertise have grown in a tremendous way, notably because of the increasing, nowadays almost ubiquitous, presence of electronic communication means in our lives.
openaire +2 more sources
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Reduction of block-transform image coding artifacts by using local statistics of transform coefficients [PDF]
, 1997 Sheung‐On Choy +2 more
openalex +1 more source