Results 81 to 90 of about 2,388,925 (316)

SNPAnalyzer 2.0: A web-based integrated workbench for linkage disequilibrium analysis and association analysis

BMC Bioinformatics, 2008
Background Since the completion of the HapMap project, huge numbers of individual genotypes have been generated from many kinds of laboratories. The efforts of finding or interpreting genetic association between disease and SNPs/haplotypes have been on ...
Kim Yujung, Lee Youngbok, Yoo Jinho, Rha Sun, Kim Yangseok   +4 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Department of Applied Mathematics and Statistics newsletter, November 4, 2023 [PDF]

, 2023
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...

core  

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

lzyqd98/GRL-Blocking-Diversity: GRL-Blocking-Diversity

<p>This product is for the GRL manuscript: Blocking Diversity: The Distinct Roles of Diabatic Heating</p ...
Zhaoyu Liu
core   +1 more source

lzyqd98/GRL_BAM-Blocking: v1.0.1

, 2023
<p>The code for exploring the relationship between BAM and blocking</p ...
Zhaoyu Liu
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Generating Cohort-specific Earnings through the Secure Query System

International Journal of Population Data Science
Objectives In collaboration with the U.S. Internal Revenue Service, we are developing a Secure Query System (SQS) to produce earnings and tax statistics for lists of individuals supplied by government agencies or academic institutions.
Amy O'Hara, Stephanie Straus, Jake Pasner   +2 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Experimental Study on Resistance Coefficient of Floating Structure

工程科学与技术, 2022
Floating structure is a new type of ecological structure suitable for the coastal and inland water conservancy projects. The application of floating structure in plain water conservancy and flood control projects will lead to the diversion of water flow ...
Zhen CUI, Zongfu FU, Yuejun CHEN
doaj