Results 101 to 110 of about 2,388,925 (316)
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Department of Applied Mathematics and Statistics newsletter, January 22, 2024 [PDF]
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...
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Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
InspireeBackground & objective: Position-specific technical demands in elite volleyball require evaluation systems that accurately reflect the tactical responsibilities of each playing role.
Anin Dita Safitri +5 more
doaj +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Department of Applied Mathematics and Statistics newsletter, September 18, 2023
, 2023 Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...
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Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Department of Applied Mathematics and Statistics newsletter, September 16, 2024 [PDF]
Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...
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Department of Applied Mathematics and Statistics newsletter, October 30, 2023 [PDF]
, 2023 Newsletter of the Department of Applied Mathematics and Statistics at Colorado School of ...
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Energy Science & EngineeringSimilarities and differences between the features related to the productivity of onshore and offshore wind energy are developed with the aid of information theory techniques complemented by normal statistics.
E. E. Vogel +3 more
doaj +1 more source