Results 71 to 80 of about 2,388,925 (316)

Pathways and modes for prevention and control of acid mine drainage-induced pollution in China

open access: yesMeitian dizhi yu kantan
Background Mining activities in polymetallic sulfide mines significantly disrupt regional hydrogeochemical equilibrium, leading to the formation of acid mine drainage (AMD).
Guo LIU   +6 more
doaj   +1 more source

Breath Analysis in Disease Diagnosis: Methodological Considerations and Applications

open access: yesMetabolites, 2014
Breath analysis is a promising field with great potential for non-invasive diagnosis of a number of disease states. Analysis of the concentrations of volatile organic compounds (VOCs) in breath with an acceptable accuracy are assessed by means of using ...
Célia Lourenço, Claire Turner
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

2022-2023 AAAL Statistics

open access: yes
Annual institutional statistics collection for AAAL member libraries.
Statistics, AAAL
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Statistics of Blocks in k-Divisible Non-Crossing Partitions [PDF]

open access: yesThe Electronic Journal of Combinatorics, 2012
We derive a formula for the expected number of blocks of a given size from a non-crossing partition chosen uniformly at random. Moreover, we refine this result subject to the restriction of having a number of blocks given.Furthermore, we generalize to $k$-divisible partitions.
openaire   +4 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Business use of information technology statistics 2013-14

open access: yes, 2015
This release includes information of business use of cloud computing for the first time, as well as internet access, social media presence and internet commerce.
Australian Bureau of Statistics
core  

2023-2024 AAAL Statistics

open access: yes
Annual institutional statistics collection for AAAL member libraries.
Statistics, AAAL
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

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