Results 111 to 120 of about 465,440 (342)
Statistical versus optimal partitioning for block entropies
Kybernetes, 2013 PurposeGiven a time‐series, what is the best partitioning of the state space in order to obtain reasonable values for the block entropies? The purpose of this paper is to provide a simple answer (an algorithm), although approximative, in connection with symbolic dynamics and statistical properties of 1‐d maps on the interval.Design/methodology ...
Mistakidis, I. +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Multidimensional item response theory and the force and motion conceptual evaluation
Physical Review Physics Education Research, 2019 Many studies have examined the structure and properties of the Force Concept Inventory (FCI); however, far less research has investigated the Force and Motion Conceptual Evaluation (FMCE).
Jie Yang, Cabot Zabriskie, John Stewart
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
On Triangle-Free v3 Configurations
MathematicsWe describe a classification algorithm of combinatorial triangle-free v3-configurations. The (non-isomorphic) triangle-free v3 configurations are classified for v∈{23,24}.
Abdullah Alazemi, Anton Betten
doaj +1 more source
Quantitative Analysis of Axonal Branch Dynamics in the Developing Nervous System.
PLoS Computational Biology, 2016 Branching is an important mechanism by which axons navigate to their targets during neural development. For instance, in the developing zebrafish retinotectal system, selective branching plays a critical role during both initial pathfinding and ...
Kelsey Chalmers +3 more
doaj +1 more source
Reduction of block-transform image coding artifacts by using local statistics of transform coefficients [PDF]
, 1997 Sheung‐On Choy +2 more
openalex +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source