Results 51 to 60 of about 706,861 (226)
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
Orthogonal main effect plans on blocks of small size [PDF]
arXiv, 2007 In this paper we define the concept of orthogonality between two factors "through another factor". Exploiting this property we have been able to obtain orthogonal main effect plans (OMEP) on non-orthogonal blocks requiring considerably smaller number of blocks than the existing methods.
arxiv
Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance
Molecular Oncology, EarlyView.In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang +8 more
wiley +1 more source
The contact process in a dynamic random environment
, 2019 We study a contact process running in a random environment in $\mathbb {Z}^d$ where sites flip, independently of each other, between blocking and nonblocking states, and the contact process is restricted to live in the space given by nonblocked sites. We
Remenik, Daniel
core +1 more source
Molecular Oncology, EarlyView.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
, 1999 The effect of baryon density on parton production processes of $gg\rightleftharpoons ggg$ and $gg\rightleftharpoons q{\bar q}$ is studied using full phase space distribution function and also with inclusion of quantum statistics i.e.
A. Dumitru +33 more
core +1 more source
Molecular Oncology, EarlyView.Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad +13 more
wiley +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Teaching Computers to Think: Analysis of Artificial Intelligence and Connect Four [PDF]
, 2012 Connect Four is a classic two person, zero-sum game in which players utilize their wits and gravity to connect four of their own pieces in a horizontal, vertical, or diagonal row while blocking their opponent’s attempt to do the same. We have constructed
Baly, Kirk +4 more
core +1 more source
Bayesian Model Selection of Stochastic Block Models [PDF]
arXiv, 2016 A central problem in analyzing networks is partitioning them into modules or communities. One of the best tools for this is the stochastic block model, which clusters vertices into blocks with statistically homogeneous pattern of links. Despite its flexibility and popularity, there has been a lack of principled statistical model selection criteria for ...
arxiv