Results 281 to 290 of about 792,108 (354)

Ruxolitinib Penetrates Blood Brain Barrier and Reduces the Cytokine Storm in Patients With Haemophagocytic Lymphohistiocytosis. [PDF]

J Cell Mol Med
Ji W, Qing K, Ren J, Xue K, Fang J, Wu S.   +5 more
europepmc   +1 more source

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

Advanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka, Ana María Pablo‐Sainz‐Ezquerra, Eva Jakljevič, Niki Ktena, Leticia Hosta‐Rigau   +4 more
wiley   +1 more source

Neuroinflammatory changes in acute myeloid leukemia: Evidence for blood-brain barrier disruption and glial activation. [PDF]

Hemasphere
Febo M, Sorcini D, Mirarchi A, Cogliati P, Stella A, Sportoletti P, Ermakova O, Mandarano M, Marchetti MC, Riccardi C, Falini B, Migliorati G, Arcuri C, Bruscoli S, Bereshchenko O.   +14 more
europepmc   +1 more source

Construction of a MOF‐Based Snap‐Top Delivery Nanosystem for Powerful Dual‐Responsive Synergistic Colitis Treatment

Advanced Science, EarlyView.
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li, Miao Xu, Heran Li, Huan Jiang, Xin Wang, Lianjun Ma, Ying‐Wei Yang   +6 more
wiley   +1 more source

Apolipoprotein D, a Novel Ligand for CD36, Is Essential for Blood-Brain Barrier Integrity. [PDF]

Circulation
Gong CX, Shi PX, Huang YJ, Dai Y, Hu LL, Cheng XF, Zhang S, He MT, Wang JH, Meng ZY, Fang YL, Wang BQ, Zhao Y, He CK, Yang GQ, Zi WJ, Qiu ZM, Li FL, Lin S, Lu H, Zhao CH, Zhang C, Liu ZY, Dong MQ, Ouyang Q, Zheng HT, Niu JQ, Mei F, Sun BL, Zhou J, Xie Q, Li FF, Yang QW.   +32 more
europepmc   +1 more source

Inflammation and the Blood‐Brain Barrier

Brain Pathology, 1991
openaire   +2 more sources

Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function

Advanced Science, EarlyView.
This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang, Wenxuan Zhao, Xiaoming Hu, Yishu Wang, Peidong Yang, Diwei Zheng, Yugang Wang, Guanghui Ma, Min Shi, Wei Wei, Shuang Wang   +10 more
wiley   +1 more source

In Silico Prediction and Validation of the Permeability of Small Molecules Across the Blood-Brain Barrier. [PDF]

Int J Mol Sci
Ajao F, de Jong-Hoogland D, Ulmschneider JP, Ulmschneider MB, Lambden E.   +4 more
europepmc   +1 more source

Progressive Hypoxia Exacerbates Breast Cancer Metastasis by Paracrine Modulation of the Blood-brain Barrier Endothelium. [PDF]

J Mol Neurosci
Brinders KA, Fisher D, Willemse C, Makhathini KB.   +3 more
europepmc   +1 more source

The triple-hit hypothesis of Alzheimer's disease: blood-brain barrier breakdown, infection, and neuroimmune activation as a unified etiological framework. [PDF]

Front Neurosci
Majdic G.
europepmc   +1 more source