Results 171 to 180 of about 779,380 (305)

Dual Physiological Barriers Bypassed by a Silk‐Based Supramolecular Protein Delivery Platform for Neuroinflammation Mitigation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
A supramolecular nanocomplex based on phenolic‐modified silk sericin is developed to deliver antioxidant enzymes across the blood–brain barrier and escape lysosomal degradation. This dual‐barrier‐crossing system reduces neuroinflammation and improves cognitive performance in Alzheimer's disease mouse model, offering a promising strategy for protein ...
Doudou Hu   +5 more
wiley   +1 more source

P40-A122 How to establish successful networking: educational training & exchange of experiences

open access: yesBMJ Open Ophthalmology, 2023
Andrea Katharina Gareiss-Lok   +5 more
doaj   +1 more source

Detection of <i>Trypanosoma cruzi</i> in a Reactive Blood Bank Sample in Sonora, Mexico. [PDF]

open access: yesTrop Med Infect Dis
Paredes-Sotelo I   +8 more
europepmc   +1 more source

Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors

open access: yesAdvanced Science, EarlyView.
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng   +12 more
wiley   +1 more source

[Blood banks].

open access: yesRevista de gastroenterologia de Mexico, 2003
Viral hepatitis is still one of the most common and severe complications of blood transfusions, with a high mortality rate. The incidence of viral hepatitis after blood transfusions has gone down, but it hasn't disappeared. In Mexico, the estimated risk of infection with HCV is 1 for every 103,000 units administered.
openaire   +1 more source

Scalable Engineering of Bio‐Manufactured Extracellular Vesicles for Selective Delivery in Ovarian Cancer Patient‐Derived Models

open access: yesAdvanced Science, EarlyView.
Engineered extracellular vesicles displaying Ephrin‐B2 selectively target Ephrin‐B4–expressing ovarian cancer cells, enabling precise delivery in patient‐derived models. This scalable bio‐manufacturing platform reveals a versatile strategy to exploit Ephrin signaling for highly specific therapeutic payload delivery and motivates exploration of tailored
Nihar Godbole   +17 more
wiley   +1 more source

Bridging the Milk Gap: Integrating a Human Milk Bank-Blood Bank Model to Reinforce Lactation Support and Neonatal Care. [PDF]

open access: yesNutrients
Barin J   +13 more
europepmc   +1 more source

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