Results 181 to 190 of about 779,380 (305)

Blood Purity and Scientific Independence : Blood Science and Postcolonial Struggles in Korea, 1926–1975

, 2019
Hyun, J.
core   +1 more source

T Cell‐Independent Role of PD‐L1 in Kidney Repair: Mitigation of Tubular DNA Damage via PD‐L1/BRCA1 Interaction Following AKI

Advanced Science, EarlyView.
PD‐L1 is primarily expressed in renal tubules and upregulated in both murine models of AKI and renal biopsy samples from patients with AKI. PD‐L1 can promote adaptive TECs repair through interacting with BRCA1, independent of its canonical immunomodulatory function of T cells, and PD‐L1 supplementation may represent a promising therapeutic strategy for
Wei Jiang, Tao‐Tao Tang, Wei‐Jie Ni, Jin‐Xuan Wei, Liang‐Yun‐Zi Jiang, Qing Yin, Yi‐Lin Zhang, Zuo‐Lin Li, Yi Wen, Xin‐Lu Wang, Jun‐Yuan Shen, Xiao‐Jun Ouyang, Ming‐Zhu Zheng, Jian Xu, Xiaofei An, Lin‐Li Lv, Bi‐Cheng Liu, Bin Wang   +17 more
wiley   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source

The Crossmatch-to-Transfusion Ratio as a Quality Indicator for Blood Bank Utilization: A Retrospective Analysis.

J Pharm Bioallied Sci
Bhatt PS, Ghelani SD, Solanki SH.
europepmc   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

Prevalence of Transfusion-Transmitted Infections and Its Association With Blood Groups Among Blood Donors at the Blood Bank of a Tertiary Care Center. [PDF]

Cureus
Khatoon Q, Arif SH.
europepmc   +1 more source

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

Establishing an Australian Bank of Cord Blood‐Derived Induced Pluripotent Stem Cell Lines: Ethics, Re‐consent, and Progress Towards Cellular Therapies

Stem Cells Translational Medicine, 2019
Keren M. Abberton, Ngaire J. Elwood
doaj   +1 more source

Prevalence trends of transfusion-transmitted infections at a tertiary private hospital blood bank in Uganda: a retrospective 6-year review (2017-2022). [PDF]

BMC Infect Dis
Kanyike AM, Kakuba F, Mayambala P, Nalunkuma R, Nakandi RM, Mulumba Y, Namulema E, Nsingo SP, Ssebuufu R.   +8 more
europepmc   +1 more source

Methodology for the Analysis of Life Science Innovation Systems (ALSIS) and its Application to Three Case Studies [PDF]

, 2012
Mastroeni, Michele, Mittra, James, Tait, Joyce   +2 more
core