The Role of CAF‐derived Vitronectin in Promoting Colorectal Cancer Progression and Immunosuppression
Cancer‐associated fibroblast (CAF)‐derived VTN upregulates SLC6A8 expression in colorectal cancer (CRC) cells and macrophages through enhanced FAK phosphorylation. This modulation significantly increases the cellular uptake of creatine and ATP, promoting cancer progression and macrophage polarization.
Jiahua Yu+5 more
wiley +1 more source
Plasma metabolic detection combined with machine learning offers a precise (area under the curve of 0.874) and high‐throughput (<30 s) diagnosis for pathologic myopia (serious myopic macular degeneration). The biomarkers indicate the pathologic myopia‐associated systemic metabolic reprogramming, which exhibits specificity for myopic macular ...
Ziheng Qi+13 more
wiley +1 more source
Prevalence and Factors Associated with transfusion-transmissible infections among blood donors in Arua regional blood bank, Uganda. [PDF]
Cwinyaai N+6 more
europepmc +1 more source
Evaluation of surrogate markers for human immunodeficiency virus infection among blood donors at the blood bank of "Hospital Universitário Regional Norte do Paraná", Londrina, PR, Brazil [PDF]
Reiche Edna Maria Vissoci+7 more
openalex
This study uses a high‐resolution DNA methylation reference panel for 19 immune cell‐types, as well as transcriptomic, metabolomic, and large population cohort data to show that age‐related epigenetic heterogeneity within monocytes correlates with inflammaging, biological age, and all‐causemortality, and does so more strongly than existing monocyte ...
Xiaolong Guo+17 more
wiley +1 more source
Evaluating the Crossmatch-to-Transfusion Ratio as a Tool for Analyzing and Optimizing Blood Bank Resource Utilization: A Retrospective Observational Study. [PDF]
Joon V+4 more
europepmc +1 more source
The storage and use of newborn babies' blood spot cards: a pubic consultation [PDF]
Dezateux, Carol+3 more
core +1 more source
Proficiency testing: impact on safety and quality of blood bank services and networks [PDF]
Vagner Castro
openalex +1 more source
Nanocatalytic Neuroprotection and Neurological Recovery Post‐Traumatic Brain Injury
This study demonstrates that combining Ce0.7Zr0.3O2 nanozymes with nimodipine enhances neuroprotection after traumatic brain injury. The therapy reduces oxidative stress, neuronal apoptosis, and improves blood–brain barrier integrity, with nanozymes effective at low doses.
Xinjie Hong+10 more
wiley +1 more source