Results 21 to 30 of about 335,559 (241)

The AIDS Blood-Transfusion Cases: A Legal and Economic Analysis of Liability [PDF]

, 1992
Through 1991 over 4,000 persons contracted AIDS through transfusion. Statutes in forty-nine states exempt blood banks from strict liability, and the usual negligence rule is weak.
Eckert, Ross D.
core   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Umbilical Cord Blood Banking [PDF]

, 2007
[À l'origine dans / Was originally part of : CRDP - Droit, biotechnologie et rapport au milieu]The umbilical cord, previously considered as waste and discarded at birth, is a source of haematopoietic stem cells. Current therapeutic uses of umbilical cord
Bordet, Sylvie, Kharaboyan, Linda, Lebrun, André   +2 more
core   +2 more sources

CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu, Wentao Chen, Yahong Wu, Zhen Guo, Jun Chen, Chen Tian, Pan Wang, Shaopeng Zeng, Bin Xu, Jing Duan, Shilong Han, Xiao Xiong, Jing Zhang   +12 more
wiley   +1 more source

Reduction of Oxidative Stress and Storage Lesions (RCSL) in Red Blood Cells: Analysis of Ascorbic Acid (AA), N-Acetylcysteine amide (AD4), and Serotonin (5-HT) [PDF]

, 2018
Oxidative stress is a common occurrence in red blood cell (RBC) storage in blood banks throughout the world. Typically RBC units stored under routine standard protocol (stored in SAGM-CPD additive solution) can only be kept up to forty-two days for ...
Gadiraju, Shanmuka
core   +1 more source

Validity and Reliability of Clinical and Patient‐Reported Outcomes in Multisystem Proteinopathy 1

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Valosin‐containing protein (VCP)‐associated multisystem proteinopathy 1 (MSP1) is caused by variants in the VCP gene. MSP1 results in various phenotypes including progressive myopathy, Paget's disease of bone, frontotemporal dementia, amyotrophic lateral sclerosis, and parkinsonism, among others.
Lindsay N. Alfano, Megan A. Iammarino, Natalie F. Reash, Linda P. Lowes, Lindsay Pietruszewski, Kathleen Adderley, Lauren Humphrey, Audrey B. Knight, Christopher L. Steiner, Melissa A. Smith, Zarife Sahenk, Anne M. Connolly, Momen Almomen, Eleonora S. D'Ambrosio, Nathan Peck, Allison Peck   +15 more
wiley   +1 more source

Model validation for a noninvasive arterial stenosis detection problem [PDF]

, 2014
Copyright @ 2013 American Institute of Mathematical SciencesA current thrust in medical research is the development of a non-invasive method for detection, localization, and characterization of an arterial stenosis (a blockage or partial blockage in an ...
A. Góral-Wójcicka, A. Karpiouk, A. O. Borisyuk, A. O. Borisyuk, A. O. Borisyuk, A. Voss, B. El-Asir, C. Kruse, C. Prado, C. Taylor, Carola Kruse, H. T. Banks, H. T. Banks, H. T. Banks, H. T. Banks, H. T. Banks, H. T. Banks, H. T. Banks, H. T. Banks, H. T. Banks, H. T. Banks, H. T. Banks, H. T. Banks, H. T. Banks, H. T. Banks, H. T. Banks, H. T. Banks, H. Thomas Banks, H. Vermarien, J. D. De Basabe, J. R. Samuels, J. Sangster, J. Semmlow, J. Semmlow, J. Verburg, J. Wloka, J.-Z. Wang, John Whiteman, L. Sandrin, M. Ainsworth, M. Akay, M. Akay, M. Akay, M. Akay, M. Akay, M. P. Brewin, M. Zia, Malcolm J. Birch, Mark P. Brewin, N. Luke, N. Owsley, N. Owsley, S. Catheline, S. Catheline, S. Chen, S. Chen, S. E. Nissen, S. E. Nissen, S. Levinson, S. Lundin, Shuhua Hu, Simon Shaw, Stephen E. Greenwald, T. Cheng, T. Deffieux, T. Pedley, T. S. Lee, V. Padmanabhan, Y. C. Fung, Zackary R. Kenz   +69 more
core   +1 more source

Herbal Formula Yi‐Fei‐Jie‐Du‐Tang Regulates Epithelial‐Mesenchymal Transition and Vasculogenic Mimicry in Lung Cancer via HIF1A‐Mediated Ferroptosis

Advanced Biology, Volume 9, Issue 3, March 2025.
Yi‐Fei‐Jie‐Du‐Tang (YFJDT), a traditional Chinese medicine, has shown potential in lung cancer treatment by targeting key pathways. This study explores the mechanisms of YFJDT using bioinformatics, xenograft models, and A549 cells, demonstrating that YFJDT downregulates HIF1A, promotes ferroptosis, and inhibits epithelial‐mesenchymal transition (EMT ...
Shanshan Wang, Die Yang, Chengjia Yuan, Yang Wu, Qingying Wang, Yongjian Wu, Xiaochun Zhang   +6 more
wiley   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

Advanced Functional Materials, EarlyView.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu, Jueun Kim, Dae‐Hyun Kim, Sewoom Baek, Suji Park, Seyong Chung, Hak‐Joon Sung   +6 more
wiley   +1 more source