Results 41 to 50 of about 43,686 (256)
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
The Pan African Medical Journal, 2017 During the 1980s the HIV/AIDS epidemic outbreak occurred. Due to the high prevalence of the disease on men who had sex with men (MSM) a lifetime ban on blood donations on men who had sex with men (MSM) was implemented.
Georgios Karamitros +2 more
doaj +1 more source
Is It Possible to Reverse the Storage-Induced Lesion of Red Blood Cells?
Frontiers in Physiology, 2018 Cold-storage of packed red blood cells (PRBCs) in the blood bank is reportedly associated with alteration in a wide range of RBC features, which change cell storage each on its own timescale.
Gregory Barshtein +4 more
doaj +1 more source
Association of Viral Load in SARS-CoV-2 Patients With Age and Gender
Frontiers in Medicine, 2021 Background: The coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is a global public health emergency.
Waleed H. Mahallawi +4 more
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Biomédica: revista del Instituto Nacional de Salud, 2016 Introducción. El virus linfotrópico de células T humanas (HTLV) de tipos 1 y 2 ocasiona trastornos clínicos asociados a enfermedades degenerativas y proliferativas.
María Isabel Bermúdez-Forero +6 more
doaj +1 more source
Status of blood transfusion service in Bhutan
Global Journal of Transfusion Medicine, 2021 Blood transfusion services in Bhutan are operated as a unit of the hospital laboratory services. There are currently 26 hospital-based blood banks that provide blood donation and transfusion services and one National Blood Bank at National Referral ...
Tshering Yangdon +2 more
doaj +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Revista Cubana de Hematología, Inmunología y Hemoterapia, 2004 Se desarrolló una investigación para estudiar la estructura y funcionamiento de 4 bancos de sangre provinciales del país, su influencia en la calidad de esta actividad y el grado de satisfacción de los donantes, con el empleo de la guía metodológica para
María E Alfonso Valdés +14 more
doaj