Results 51 to 60 of about 47,790 (302)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Association of Viral Load in SARS-CoV-2 Patients With Age and Gender

open access: yesFrontiers in Medicine, 2021
Background: The coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is a global public health emergency.
Waleed H. Mahallawi   +4 more
doaj   +1 more source

Investigation of the Immature Stage of the Cord Blood Banks and Their Regulation in China

open access: yes, 2008
Cord blood banks (CBBs) collect umbilical cord blood and isolate therefrom the stem cells which may be transplanted into patients serving treatment of many kinds of serious diseases.
Liu, Yinliang
core   +1 more source

Increased sensitivity for detecting malaria parasites in human umbilical cord blood using scaled-up DNA preparation. [PDF]

open access: yes, 2012
BACKGROUND: All mothers donating umbilical cord blood units to the NHS cord blood bank undergo an assessment for the likelihood of prior exposure to malaria infection.
Fiona Regan   +14 more
core   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

The ban on blood donation on men who have sex with men: time to rethink and reassess an outdated policy

open access: yesThe Pan African Medical Journal, 2017
During the 1980s the HIV/AIDS epidemic outbreak occurred. Due to the high prevalence of the disease on men who had sex with men (MSM) a lifetime ban on blood donations on men who had sex with men (MSM) was implemented.
Georgios Karamitros   +2 more
doaj   +1 more source

Is It Possible to Reverse the Storage-Induced Lesion of Red Blood Cells?

open access: yesFrontiers in Physiology, 2018
Cold-storage of packed red blood cells (PRBCs) in the blood bank is reportedly associated with alteration in a wide range of RBC features, which change cell storage each on its own timescale.
Gregory Barshtein   +4 more
doaj   +1 more source

The cost of blood in paediatric oncology patients [PDF]

open access: yes, 2016
Introduction: Consumption of blood products is significant aiming to treat low cell counts and improve quality of life however 9% to 44% of the total consumption in centres abroad are unjustified.
Debattista, Daniel   +5 more
core  

The role of failure modes and effects analysis in showing the benefits of automation in the blood bank

open access: yes, 2013
BACKGROUND: Failure modes and effects analysis (FMEA) is a risk management tool used by the manufacturing industry but now being applied in laboratories.
김신영, 김현옥
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

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