Results 111 to 120 of about 17,462,775 (406)

Exosomes from red blood cell units bind to monocytes and induce proinflammatory cytokines, boosting T-cell responses in vitro.

open access: yesBlood, 2014
Extracellular vesicles (EVs) are small, double membrane vesicles derived from leukocytes, platelets, and cells of other tissues under physiological or pathological conditions.
A. Danesh   +7 more
semanticscholar   +1 more source

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Angiogenesis: A Model of Cell Differentiation [PDF]

open access: yes, 2000
Angiogenesis is the formation of blood vessels, and is of great importance in the growth of tumours. Attempts have been made to desgin experiments in petri-dishes that mimic the 'Conditions of tumour growth. The first of the experiments is the 'matrigel'
Hinch, R.
core  

Rotational behavior of red blood cells in suspension---a mesoscale simulation study

open access: yes, 2010
The nature of blood as a suspension of red blood cells makes computational hemodynamics a demanding task. Our coarse-grained blood model, which builds on a lattice Boltzmann method for soft particle suspensions, enables the study of the collective ...
Harting, Jens   +3 more
core   +1 more source

Functional characterization of reappearing B cells after anti-CD20 treatment of CNS autoimmune disease. [PDF]

open access: yes, 2018
The anti-CD20 antibody ocrelizumab, approved for treatment of multiple sclerosis, leads to rapid elimination of B cells from the blood. The extent of B cell depletion and kinetics of their recovery in different immune compartments is largely unknown ...
Bernard, Claude CA   +9 more
core   +1 more source

The adaptability of red blood cells [PDF]

open access: yesCardiovascular Diabetology, 2013
The most important function of red blood cells (RBCs) is the carrying of oxygen, but they are also involved in inflammatory processes and during coagulation. RBCs are extremely deformable and elastic, as they are exposed to shear forces as they travel through the vascular system.
openaire   +4 more sources

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Imaging human blood cells in vivo with oblique back-illumination capillaroscopy [PDF]

open access: yesarXiv, 2020
We present a non-invasive, label-free method of imaging blood cells flowing through human capillaries in vivo using oblique back-illumination capillaroscopy (OBC). Green light illumination allows simultaneous phase and absorption contrast, enhancing the ability to distinguish red and white blood cells.
arxiv  

Of pools, oceans, and the Dead Sea. [PDF]

open access: yes, 2017
In a comprehensive study in this issue of Blood, Carden and colleagues describe the importance of the tonicity of IV fluids used in the treatment of patients with sickle cell disease (SCD) during vaso-occlusive crises (VOCs).
Ballas, Samir K.
core   +2 more sources

Selection of unrelated donors and cord blood units for hematopoietic cell transplantation: guidelines from the NMDP/CIBMTR

open access: yesBlood, 2019
Allogeneic hematopoietic cell transplantation involves consideration of both donor and recipient characteristics to guide the selection of a suitable graft.
J. Dehn   +15 more
semanticscholar   +1 more source

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