Results 181 to 190 of about 4,638,350 (355)

Small-Molecule-Directed Mpl Signaling Can Complement Growth Factors to Selectively Expand Genetically Modified Cord Blood Cells [PDF]

, 2003
Robert E. Richard, C. Anthony Blau
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Blood Cell Mitochondrial Respiration Increases With Age and Varies by Sex in Healthy Adults. [PDF]

Aging Cell
Phang HJ, Bergstrom J, Keri B, Heimler SR, Dozier S, Scandalis LM, Wing D, Moreno D, Sun NN, Molina AJA.   +9 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Diversity Analysis of Fecal Microbiota in Goats Driven by White Blood Cell Count. [PDF]

Microorganisms
Zeng M, Zhou H, Wu Q, Wang K, Liu H, Yang Y, Peng W, Chen A, Deng X, Ji C, Zhang X, Han J.   +11 more
europepmc   +1 more source

Prognostic Accuracy of Blood Cell Count Ratios in Predicting Adverse Outcomes in Crush Syndrome Patients [PDF]

Taner Karlıdağ, Olgun Bingöl, Baran Sarıkaya, Ömer Halit Keskin, Atahan Durğal, Güzelali Özdemir   +5 more
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The role of the spleen in red blood cell loss caused by malaria: A mathematical model. [PDF]

PLoS Comput Biol
Moss R, Dini S, Kho S, Barber BE, Buffet PA, Rajasekhar M, Price DJ, Anstey NM, Simpson JA.   +8 more
europepmc   +1 more source

Human Immunodeficiency Virus (HIV) Infection of Human Placental Cord Blood CD34+ Stem Cells and Their Progeny [PDF]

, 1999
Deepa Hariharan, Yuan Li, Donald E. Campbell, Li Song, Joann Cutilli, Steven D. Douglas, Wen‐Zhe Ho   +6 more
openalex   +1 more source