Results 21 to 30 of about 17,678,936 (383)

Efficient RNA drug delivery using red blood cell extracellular vesicles

open access: yesNature Communications, 2018
Most of the current methods for programmable RNA drug therapies are unsuitable for the clinic due to low uptake efficiency and high cytotoxicity.
Waqas Muhammad Usman   +16 more
semanticscholar   +1 more source

Effect of mycophenolate mofetil on the white blood cell count and the frequency of infection in systemic lupus erythematosus. [PDF]

open access: yes, 2015
Leukopenia is a common manifestation of SLE. Addition of immunosuppressive therapy in a SLE patient who is already leukopenic is a clinical concern. It could worsen leukopenia, increase the risk of infection, or both. The aim of this study was to analyze
Magder, Laurence S.   +2 more
core   +2 more sources

Transcriptomic data from two primary cell models stimulating human monocytes suggest inhibition of oxidative phosphorylation and mitochondrial function by N. meningitidis which is partially up-regulated by IL-10

open access: yesBMC Immunology, 2017
Background Biological interpretation of DNA microarray data may differ depending on underlying assumptions and statistical tests of bioinformatics tools used.
Unni Gopinathan   +6 more
doaj   +1 more source

An Imaging Flow Cytometry Method to Measure Citrullination of H4 Histone as a Read-out for Neutrophil Extracellular Traps Formation

open access: yesBio-Protocol, 2021
The formation of neutrophil extracellular traps (NETs) is thought to play a critical role in infections and propagating sterile inflammation. Histone citrullination is an essential and early step in NETs formation, detectable prior to the formation of ...
Emilia Barbu   +3 more
doaj   +1 more source

Combining Convolutional Neural Network With Recursive Neural Network for Blood Cell Image Classification

open access: yesIEEE Access, 2018
The diagnosis of blood-related diseases involves the identification and characterization of a patient’s blood sample. As such, automated methods for detecting and classifying the types of blood cells have important medical applications in this field ...
G. Liang   +3 more
semanticscholar   +1 more source

Rapid and label-free identification of single leukemia cells from blood in a high-density microfluidic trapping array by fluorescence lifetime imaging microscopy. [PDF]

open access: yes, 2018
The rapid screening and isolation of single leukemia cells from blood has become critical for early leukemia detection and tumor heterogeneity interrogation. However, due to the size overlap between leukemia cells and the more abundant white blood cells (
Digman, Michelle A   +4 more
core   +1 more source

Why regenerative stem cell medicine progresses slower than expected [PDF]

open access: yes, 2014
Stem cell research has been acclaimed to revolutionize the future of medicine, and to offer new treatments for previously incurable diseases. Despite years of research, however, the therapeutic potential of stem cell research has not yet been fully ...
Amariglio   +16 more
core   +1 more source

Bloodstream infections due to Carbapenem-Resistant Enterobacteriaceae in hematological patients: assessment of risk factors for mortality and treatment options

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2023
Purpose Bloodstream infection (BSI) caused by Carbapenem-Resistant Enterobacteriaceae (CRE) are associated with poor outcomes in hematological patients.
Lining Zhang   +12 more
doaj   +1 more source

Accelerated epigenetic aging in Werner syndrome. [PDF]

open access: yes, 2017
Individuals suffering from Werner syndrome (WS) exhibit many clinical signs of accelerated aging. While the underlying constitutional mutation leads to accelerated rates of DNA damage, it is not yet known whether WS is also associated with an increased ...
Flunkert, Julia   +5 more
core   +1 more source

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