Results 81 to 90 of about 17,678,936 (383)
Current and future treatment strategies in chronic lymphocytic leukemia
Journal of Hematology & Oncology, 2021 Treatment decisions for patients with chronic lymphocytic leukemia (CLL) are dependent on symptoms and classification into high-, medium-, or low-risk categories. The prognosis for CLL hinges, in part, on the presence or absence of less-favorable genetic
Krish Patel, John M. Pagel
doaj +1 more source
Of pools, oceans, and the Dead Sea. [PDF]
, 2017 In a comprehensive study in this issue of Blood, Carden and colleagues describe the importance of the tonicity of IV fluids used in the treatment of patients with sickle cell disease (SCD) during vaso-occlusive crises (VOCs).
Ballas, Samir K.
core +2 more sources
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
Red blood cell as an adaptive optofluidic microlens
Nature Communications, 2015 The perspective of using live cells as lenses could open new revolutionary and intriguing scenarios in the future of biophotonics and biomedical sciences for endoscopic vision, local laser treatments via optical fibres and diagnostics.
L. Miccio +4 more
semanticscholar +1 more source
Advances in drug delivery systems utilizing blood cells and their membrane-derived microvesicles
Drug DeliveryThe advancement of drug delivery systems (DDSs) in recent decades has demonstrated significant potential in enhancing the efficacy of pharmacological agents.
Andong He +3 more
doaj +1 more source
Angiogenesis: A Model of Cell Differentiation [PDF]
, 2000 Angiogenesis is the formation of blood vessels, and is of great importance in the growth of tumours. Attempts have been made to desgin experiments in petri-dishes that mimic the 'Conditions of tumour growth. The first of the experiments is the 'matrigel'
Hinch, R.
core
Rotational behavior of red blood cells in suspension---a mesoscale simulation study
, 2010 The nature of blood as a suspension of red blood cells makes computational hemodynamics a demanding task. Our coarse-grained blood model, which builds on a lattice Boltzmann method for soft particle suspensions, enables the study of the collective ...
Harting, Jens +3 more
core +1 more source
Drugs for preventing red blood cell dehydration in people with sickle cell disease. [PDF]
, 2016 BACKGROUND: Sickle cell disease is an inherited disorder of hemoglobin, resulting in abnormal red blood cells. These are rigid and may block blood vessels leading to acute painful crises and other complications.
Ballas, Samir K., Nagalla, Srikanth
core +2 more sources
FEBS Letters, EarlyView.The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp +5 more
wiley +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source