Results 11 to 20 of about 17,492,293 (382)

Sustained immunotolerance in multiple sclerosis after stem cell transplant

open access: yesAnnals of Clinical and Translational Neurology, 2022
Objective Autologous haematopoietic stem cell transplantation (AHSCT) has the potential to induce sustained periods of disease remission in multiple sclerosis (MS), which is an inflammatory disease of the central nervous system (CNS) characterised by ...
Malini Visweswaran   +9 more
doaj   +1 more source

Single-cell transcriptomic landscape of human blood cells

open access: yesNational Science Review, 2020
High throughput single-cell RNA-seq has been successfully implemented to dissect the cellular and molecular features underlying hematopoiesis. However, an elaborate and comprehensive transcriptome reference of the whole blood system is lacking.
Xiaowei Xie   +29 more
semanticscholar   +1 more source

Grandmaternal cells in cord blood [PDF]

open access: yeseBioMedicine, 2021
During pregnancy a feto-maternal exchange of cells through the placenta conducts to maternal microchimerism (Mc) in the child and fetal Mc in the mother. Because of this bidirectional traffic of cells, pregnant women have also acquired maternal cells in utero from their mother and could transfer grandmaternal (GdM) cells to their child through the ...
Karlin R. Karlmark   +12 more
openaire   +4 more sources

New-Generation Ektacytometry Study of Red Blood Cells in Different Hemoglobinopathies and Thalassemia

open access: yesThalassemia Reports, 2023
Next-generation ektacytometry provided by the osmoscan module of the Laser Optical Rotational Red Cell Analyser (LoRRca) MaxSis is, so far, one of the best complementary diagnostic tools for congenital rare anaemias due to red blood cell defects. Osmotic
Elena Krishnevskaya   +4 more
doaj   +1 more source

DARS2 overexpression is associated with PET/CT metabolic parameters and affects glycolytic activity in lung adenocarcinoma

open access: yesJournal of Translational Medicine, 2023
Background This study investigated the correlation between the expression of DARS2 and metabolic parameters of 18F-FDG PET/CT, and explored the potential mechanisms of DARS2 affecting the proliferation and glycolysis of lung adenocarcinoma (LUAD) cells ...
Xu-Sheng Liu   +8 more
doaj   +1 more source

Impact of glucocorticoids on short-term and long-term outcomes in patients with relapsed/refractory multiple myeloma treated with CAR-T therapy

open access: yesFrontiers in Immunology, 2022
BackgroundGlucocorticoids (GCs) are often used to treat cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS). The effects of GCs on the efficacy of CAR-T cell treatment in relapsed/refractory multiple myeloma
Xue Wang   +36 more
doaj   +1 more source

Blood Cells and Blood Cell Development in the Animal Kingdom [PDF]

open access: yesAnnual Review of Cell and Developmental Biology, 2006
Recent findings strongly suggest that the molecular pathways involved in the development and function of blood cells are highly conserved among vertebrates and various invertebrate phyla. This has led to a renewed interest regarding homologies between blood cell types and their developmental origin among different animals.
openaire   +4 more sources

Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial.

open access: yesJournal of the American Medical Association (JAMA), 2015
IMPORTANCE Severely injured patients experiencing hemorrhagic shock often require massive transfusion. Earlier transfusion with higher blood product ratios (plasma, platelets, and red blood cells), defined as damage control resuscitation, has been ...
J. Holcomb   +31 more
semanticscholar   +1 more source

Autophagy in cells of the blood

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2009
Autophagy is a conserved proteolytic mechanism that degrades cytoplasmic material including cell organelles. The importance of autophagy for cell homeostasis and survival has long been appreciated. Recent data suggest that autophagy is also involved in non-metabolic functions that particularly concern blood cells.
Shida Yousefi, Hans-Uwe Simon
openaire   +3 more sources

The Red Blood Cells on the Move! [PDF]

open access: yesFrontiers in Physiology, 2018
Following the steps of the founders of modern red blood cell (RBC) research (e.g., Ørskov, 1935; Wilbrandt, 1937; Cohn and Cohn, 1939; Ponder, 1948; Pauling et al., 1949), we answer to the growing need of a platform to share and discuss the new findings, argue and move forward in our understanding of these amazing cells.
Bogdanova, Anna, Kaestner, Lars
openaire   +5 more sources

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