Red Blood Cells: Chasing Interactions [PDF]
Human red blood cells (RBC) are highly differentiated cells that have lost all organelles and most intracellular machineries during their maturation process. RBC are fundamental for the nearly all basic physiologic dynamics and they are key cells in the body's respiratory system by being responsible for the oxygen transport to all cells and tissues ...
Virginia Pretini +8 more
openaire +5 more sources
BackgroundGlucocorticoids (GCs) are often used to treat cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS). The effects of GCs on the efficacy of CAR-T cell treatment in relapsed/refractory multiple myeloma
Xue Wang +36 more
doaj +1 more source
M-DC8+leukocytes - A novel human dendritic cell population [PDF]
Dendritic cells (DC) constitute a heterogeneous leukocyte population having in common a unique capacity to induce primary T cell responses and are therefore most attractive candidates for immunomodulatory strategies.
Federle, Christine +5 more
core +2 more sources
Following red blood cells in a pulmonary capillary [PDF]
The red blood cells or erythrocytes are biconcave shaped cells and consist mostly in a membrane delimiting a cytosol with a high concentration in hemoglobin.
B. Maury +6 more
core +2 more sources
An Erg-driven transcriptional program controls B cell lymphopoiesis
B cell development is tightly regulated in a stepwise manner to ensure proper generation of repertoire diversity via somatic gene rearrangements. Here, the authors show that a transcription factor, Erg, functions at the earliest stage to critically ...
Ashley P. Ng +27 more
doaj +1 more source
Rare-cell enrichment by a rapid, label-free, ultrasonic isopycnic technique for medical diagnostics [PDF]
One significant challenge in medical diagnostics lies in the development of label-free methods to separate different cells within complex biological samples.
Bell +18 more
core +1 more source
Background Acute myeloid leukemia (AML) is a heterogenous hematological malignancy with poor long-term survival. New drugs which improve the outcome of AML patients are urgently required.
Hayaa Moeed Alhuthali +4 more
doaj +1 more source
Modelling hematopoiesis mediated by growth factors with applications to periodic hematological diseases [PDF]
Hematopoiesis is a complex biological process that leads to the production and regulation of blood cells. It is based upon differentiation of stem cells under the action of growth factors.
Adimy, Mostafa +2 more
core +5 more sources
Improved arteriogenesis with simultaneous skeletal muscle repair in ischemic tissue by SCL plus multipotent adult progenitor cell clones from peripheral blood [PDF]
Background: The CD34- murine stem cell line RM26 cloned from peripheral blood mononuclear cells has been shown to generate hematopoietic progeny in lethally irradiated animals.
Gottgens, Berthold +7 more
core +1 more source
Differential effects of α4β7 and GPR15 on homing of effector and regulatory T cells from patients with UC to the inflamed gut in vivo [PDF]
Objective: Gut homing of lymphocytes via adhesion molecules has recently emerged as new target for therapy in inflammatory bowel diseases. We aimed to analyze the in vivo homing of effector (Teff) and regulatory (Treg) T cells to the inflamed gut via ...
Agace +64 more
core +1 more source

