Results 31 to 40 of about 9,259,664 (317)

Dasatinib inhibits CXCR4 signaling in chronic lymphocytic leukaemia cells and impairs migration towards CXCL12 [PDF]

, 2012
Chemokines and their ligands play a critical role in enabling chronic lymphocytic leukaemia (CLL) cells access to protective microenvironmental niches within tissues, ultimately resulting in chemoresistance and relapse: disruption of these signaling ...
McCaig, Alison M., Alison M McCaig, Alison M. Mccaig, Cosimo Emilio, Alison M. Michie, Leach Michael T., Alison M Michie, Emilio Cosimo, Michael T. Leach, McCaig Alison M., Michael T Leach, Michie, Alison M., Michie Alison M., Cosimo, Emilio, Leach, Michael T.   +14 more
core   +1 more source

Autophagy in cells of the blood

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2009
Autophagy is a conserved proteolytic mechanism that degrades cytoplasmic material including cell organelles. The importance of autophagy for cell homeostasis and survival has long been appreciated. Recent data suggest that autophagy is also involved in non-metabolic functions that particularly concern blood cells.
Yousefi, Shida, Simon, Hans-Uwe
openaire   +4 more sources

Immunotherapies targeting GPRC5D in relapsed or refractory multiple myeloma: latest updates from 2022 ASH Annual Meeting

Journal of Hematology & Oncology, 2023
B cell maturation antigen (BCMA)-targeted immunotherapy has shown unprecedented results in the treatment of relapsed or refractory (R/R) multiple myeloma (MM).
Jieyun Xia, Zhenyu Li, Kailin Xu
doaj   +1 more source

A combination of pre-infusion serum ferritin, CRP and IL-6 predicts outcome in relapsed/refractory multiple myeloma patients treated with CAR-T cells

Frontiers in Immunology, 2023
BackgroundChimeric antigen receptor - T (CAR-T) cell therapy has shown remarkable efficacy in patients with relapsed/refractory multiple myeloma (R/R MM).
Yang Liu, Yang Liu, Yang Liu, Xingxing Jie, Xingxing Jie, Xingxing Jie, Li Nian, Li Nian, Li Nian, Ying Wang, Ying Wang, Ying Wang, Congyue Wang, Congyue Wang, Congyue Wang, Jin Ma, Jin Ma, Jin Ma, Jingjing Jiang, Jingjing Jiang, Jingjing Jiang, Qingyun Wu, Qingyun Wu, Qingyun Wu, Jianlin Qiao, Jianlin Qiao, Jianlin Qiao, Wei Chen, Wei Chen, Wei Chen, Jiang Cao, Jiang Cao, Jiang Cao, Zhiling Yan, Zhiling Yan, Zhiling Yan, Ming Shi, Hai Cheng, Hai Cheng, Hai Cheng, Feng Zhu, Feng Zhu, Feng Zhu, Wei Sang, Wei Sang, Wei Sang, Depeng Li, Depeng Li, Depeng Li, Chong Chen, Chong Chen, Chong Chen, Kailin Xu, Kailin Xu, Kailin Xu, Zhenyu Li, Zhenyu Li, Zhenyu Li   +57 more
doaj   +1 more source

Freeze-thaw lysates of Plasmodium falciparum-infected red blood cells induce differentiation of functionally competent regulatory T cells from memory T cells. [PDF]

, 2012
In addition to naturally occurring regulatory T (nTreg) cells derived from the thymus, functionally competent Treg cells can be induced in vitro from peripheral blood lymphocytes in response to TCR stimulation with cytokine costimulation.
Finney, Olivia C, Riley, Eleanor M, Finney, OC, Lawrence, Emma, Gray, Alice P, Njie, Madi, Walther, M, Walther, Michael, Riley, EM, Gray, AP, Lawrence, E, Njie, M   +11 more
core   +1 more source

EPC infusion ameliorates acute graft-versus-host disease-related endothelial injury after allogeneic bone marrow transplantation

Frontiers in Immunology, 2022
IntroductionGraft-versus-host disease (GVHD) damages vascular endothelium. Endothelial progenitor cell (EPC) can differentiate to endothelial cell and promote angiogenesis, but its role in endothelial damage in GVHD is unclear.MethodsIn this study, we ...
Weiwei Wang, Weiwei Wang, Weiwei Wang, Yali Ye, Yali Ye, Yali Ye, Yuwei Du, Yuwei Du, Yuwei Du, Zhengqing Xu, Zhengqing Xu, Zhengqing Xu, Ke Yuan, Ke Yuan, Ke Yuan, Yizhou Wang, Yizhou Wang, Yizhou Wang, Seyram Yao Adzraku, Seyram Yao Adzraku, Seyram Yao Adzraku, Yue Li, Yue Li, Yue Li, Kailin Xu, Kailin Xu, Kailin Xu, Jianlin Qiao, Jianlin Qiao, Jianlin Qiao, Wen Ju, Wen Ju, Wen Ju, Lingyu Zeng, Lingyu Zeng, Lingyu Zeng   +35 more
doaj   +1 more source

A same‐day assay predicts apoptotic response to combined BCL‐2 and MCL‐1 BH3‐mimetic targeting in multiple myeloma cells

eJHaem, 2021
Recent advances in treatment options for multiple myeloma (MM) have positive impact on patient survival. However, there is a short fall of rapid and reliable assays that can predict patient response to novel agents.
Martin Grundy, Firas Al‐Kaisi, Joanna Cull, Cathy Williams, Dean Smith, Claire H. Seedhouse   +5 more
doaj   +1 more source

Separation of blood cells with differing deformability using deterministic lateral displacement [PDF]

, 2014
Determining cell mechanical properties is increasingly recognized as a marker-free way to characterize and separate biological cells. This emerging realization has led to the development of a plethora of appropriate measurement techniques. Here, we use a
Nuria Vergara-Irigaray, Whyte, G, Ekpenyong, Andrew, Guck, Jochen, Guck, J, Andrew Ekpenyong, David Holmes, Bailey, Joe, Duke, T, Ekpenyong, A., Bailey, J, Jochen Guck, Vergara-Irigaray, N, Guck, J., Duke, T., Joe Bailey, Vergara-Irigaray, Nuria, Tom Duke, Holmes, D., Holmes, David, Vergara-Irigaray, N., Duke, Tom, Whyte, G., Graeme Whyte, Whyte, Graeme, Holmes, D, Bailey, J., Ekpenyong, A   +27 more
core   +1 more source

Renal pericytes: regulators of medullary blood flow [PDF]

, 2012
Regulation of medullary blood flow (MBF) is essential in maintaining normal kidney function. Blood flow to the medulla is supplied by the descending vasa recta (DVR), which arise from the efferent arterioles of juxtamedullary glomeruli.
Peppiatt-Wildman, Claire M., Kennedy-Lydon, T M, Wildman, S S P, Peppiatt-Wildman, C M, Peppiatt‐Wildman, C. M., Kennedy‐Lydon, T. M., Wildman, Scott S.P., Kennedy-Lydon, T. M., Crawford, C., Crawford, C, Wildman, S. S. P.   +10 more
core   +1 more source

THE BLOOD-CELLS IN ANÆMIA. [PDF]

The Lancet, 1881
n ...
openaire   +1 more source