Results 11 to 20 of about 4,253,616 (306)
Modelling hematopoiesis mediated by growth factors with applications to periodic hematological diseases [PDF]
, 2006 Hematopoiesis is a complex biological process that leads to the production and regulation of blood cells. It is based upon differentiation of stem cells under the action of growth factors.
Adimy, Mostafa +2 more
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Blood Cells and Blood Cell Development in the Animal Kingdom [PDF]
Annual Review of Cell and Developmental Biology, 2006 Recent findings strongly suggest that the molecular pathways involved in the development and function of blood cells are highly conserved among vertebrates and various invertebrate phyla. This has led to a renewed interest regarding homologies between blood cell types and their developmental origin among different animals.
openaire +3 more sources
An Erg-driven transcriptional program controls B cell lymphopoiesis
Nature Communications, 2020 B cell development is tightly regulated in a stepwise manner to ensure proper generation of repertoire diversity via somatic gene rearrangements. Here, the authors show that a transcription factor, Erg, functions at the earliest stage to critically ...
Ashley P. Ng +27 more
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Frontiers in Immunology, 2022 BackgroundGlucocorticoids (GCs) are often used to treat cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS). The effects of GCs on the efficacy of CAR-T cell treatment in relapsed/refractory multiple myeloma
Xue Wang +36 more
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Classification of large circulating tumor cells isolated with ultra-high throughput microfluidic Vortex technology. [PDF]
, 2016 Circulating tumor cells (CTCs) are emerging as rare but clinically significant non-invasive cellular biomarkers for cancer patient prognosis, treatment selection, and treatment monitoring.
Che, James +15 more
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M-DC8+leukocytes - A novel human dendritic cell population [PDF]
, 1999 Dendritic cells (DC) constitute a heterogeneous leukocyte population having in common a unique capacity to induce primary T cell responses and are therefore most attractive candidates for immunomodulatory strategies.
Federle, Christine +5 more
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BMC Cancer, 2020 Background Acute myeloid leukemia (AML) is a heterogenous hematological malignancy with poor long-term survival. New drugs which improve the outcome of AML patients are urgently required.
Hayaa Moeed Alhuthali +4 more
doaj +1 more source
Improved arteriogenesis with simultaneous skeletal muscle repair in ischemic tissue by SCL plus multipotent adult progenitor cell clones from peripheral blood [PDF]
, 2004 Background: The CD34- murine stem cell line RM26 cloned from peripheral blood mononuclear cells has been shown to generate hematopoietic progeny in lethally irradiated animals.
Gottgens, Berthold +7 more
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Functional characterization of reappearing B cells after anti-CD20 treatment of CNS autoimmune disease. [PDF]
, 2018 The anti-CD20 antibody ocrelizumab, approved for treatment of multiple sclerosis, leads to rapid elimination of B cells from the blood. The extent of B cell depletion and kinetics of their recovery in different immune compartments is largely unknown ...
Bernard, Claude CA +9 more
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Journal of Hematology & Oncology, 2023 B cell maturation antigen (BCMA)-targeted immunotherapy has shown unprecedented results in the treatment of relapsed or refractory (R/R) multiple myeloma (MM).
Jieyun Xia, Zhenyu Li, Kailin Xu
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