Results 181 to 190 of about 2,523,312 (291)

Blood Coagulation Factor IX: Structure, Function, and Regulation. [PDF]

IUBMB Life
Ivanciu L, Camire RM.
europepmc   +1 more source

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

Advanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu, Wenbo Geng, Qinjin Dai, Wanyun Zhang, Yuxian Lai, Pei Zhang, Chunjiang Zhou, Yinuo Wang, Qingfeng Cao, Xiang Luo, Yujie Lai, Changwei Huang, Peizeng Yang   +12 more
wiley   +1 more source

Low-temperature plasma efficiently promotes blood coagulation with less thermal injury in porcine models. [PDF]

Sci Rep
Wei Y, Li Y, Zheng H, Zhang B, Li Y, Zhang Y, Xu Z, Xu A, Jin S, Fang Z, Zhang L, Zhao Y, Zhu L, Li X.   +13 more
europepmc   +1 more source

Lanthanum Carbonate Nanosheets Based Colloidal Hydrogel for Modulating Innate & Adaptive Tumor Immunotherapy by Augmented Cellular Pyroptosis

Advanced Science, EarlyView.
The Gela/decitabine/La2(CO3)3 colloidal (GDLC) hydrogel developed here could reverse the epigenetic silencing of the GSDME gene by the synergistic interaction between DAC and La3+, while concurrently activating caspase‐3, thus facilitating pyroptosis induction under the tumor microenvironment.
Yang Hong, Haitao Wu, Weitao Wang, Xuan Zhang, Qian Chen, Yaoyu Hu, Zhengbao Zha   +6 more
wiley   +1 more source

Blood Coagulation Favors Anti-Inflammatory Immune Responses in Whole Blood. [PDF]

Hematol Rep
Seledtsov VI, Pyshenko AA, Lyubavskaya TY, Seledtsova IA, von Delwig AA.   +4 more
europepmc   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Diagnostic Value of Protein C Depletion in Pathologies Associated with the Activation of the Blood Coagulation System. [PDF]

Int J Mol Sci
Korolova DS, Platonova TM, Gornytska OV, Chernyshenko V, Korchynskyi O, Komisarenko SV.   +5 more
europepmc   +1 more source

TRIM28‐Derived Peptide Exerts Anti‐Tumor Roles by Stabilizing Tumor Suppressive BRD7 Protein in Multiple Cancers

Advanced Science, EarlyView.
An α‐helical peptide, TAB12, designed to mimic the TRIM28 binding interface, competitively disrupts the TRIM28‐BRD7 interaction, thereby blocking ubiquitin‐mediated degradation of the tumor suppressor BRD7. This stabilization unleashes potent anti‐tumor effects across multiple tumor types with a favorable safety profile, offering a feasible strategy ...
Qingqing Wei, Changning Xue, Mengna Li, Jianxia Wei, Lemei Zheng, Shipeng Chen, Yijie Wang, Yumei Duan, Yanwei Luo, Wei Xiong, Ming Zhou   +10 more
wiley   +1 more source

Uncovering position-specific patterns in codon and codon-pair usage in candidate genes associated with blood coagulation diseases. [PDF]

NAR Genom Bioinform
Clement NJ, Hamasaki-Katagiri N, Lin B, Komar AA, DiCuccio M, Bar H, Kimchi-Sarfaty C.   +6 more
europepmc   +1 more source

Receptogenesis in a Vascularized Robotic Embodiment

Advanced Science, EarlyView.
Functional augmentation of situated robots via ex novo hardware generation extends physical adaptability. Drawing inspiration from open circulatory systems for mass and function redistribution, this study presents a vascularized robotic composite exhibiting receptogenesis ‐ the on‐demand construction of sensors ‐ from internal fluid reserves based on ...
Kadri‐Ann Pankratov, Leonid Zinatullin, Hans Priks, Adele Metsniit, Urmas Johanson, Tarmo Tamm, Alvo Aabloo, Edoardo Sinibaldi, Indrek Must   +8 more
wiley   +1 more source