Results 191 to 200 of about 183,484 (340)

Assessing the therapeutic potential of Tirzepatide in modulating inflammatory responses and mitigating acute pancreatitis

Animal Models and Experimental Medicine, EarlyView.
Tirzepatide: A peptide‐based GLP‐1/GIP receptor agonist, tested on L‐Arginine‐induced pancreatitis. Lipase/Amylase Levels: Initially elevated due to inflammation but normalized with Tirzepatide. Inflammatory Response: Reduction in pro‐inflammatory cytokines (IL‐6) and enhancement of anti‐inflammatory cytokines (IL‐4, IL‐10).
Razan Alawaji, Mohamed S. Abdel‐Bakky, Hussein M. Ali, Miad A. Aljuhani, Abdulaziz Arif A. Alshammari, Hashim K. Kamal, Maamoun M. K. Khoja, Kholoud Alsehemi, Mennatallah A. Korani, Eman S. Said   +9 more
wiley   +1 more source

Correlation analysis between frequency of gastrointestinal bleeding episodes and abnormal coagulation indexes in digestive system tumors. [PDF]

Sci Rep
Shaoqing A, Jun G, Jia W, Jie L.
europepmc   +1 more source

Pharmacological effect of Allium sativum on coagulation, blood pressure, diabetic nephropathy, neurological disorders, spermatogenesis, antibacterial effects

, 2019
Seyyed Abbas Hashemi, Sayeh Ghorbanoghli, Aliasghar Manouchehri, Mahdi Babaei Hatkehlouei   +3 more
openalex   +1 more source

Irisin‐Loaded Dissolving Microneedles Promote Rapid Wound Healing

Advanced NanoBiomed Research, EarlyView.
Schematic of effective wound healing facilitated by water‐degradable microneedles loaded with irisin that enhance irisin penetration, fibroblast migration, differentiation, and extracellular matrix synthesis at the wound site. Irisin, an exercise‐induced myokine with anti‐inflammatory and regenerative activity, is incorporated into dissolving poly ...
Yu‐Chi Pan, Sheng‐Hua Wu, Hung‐Pei Tsai, Ming‐Hong Tai, Chien‐Ju Lin, Hung‐Wei Yang, Shu‐Hung Huang   +6 more
wiley   +1 more source

Placental Dysfunction Is Associated with Dysregulated Fibrinolytic System Activation. [PDF]

Int J Mol Sci
Yatsenko T, Us I, Korolova D, Zhuk S, Dziuba H, Nalbat A, Kharchenko S, Vari SG, Chernyshenko V.   +8 more
europepmc   +1 more source

Thromboelastography variables, immune markers, and endothelial factors associated with shock and NPMODS in children with severe sepsis [PDF]

, 2019
Ignell, Steven P, Lin, John C, Saini, Arun, Spinella, Philip C   +3 more
core   +1 more source

Antiphospholipid Syndrome: An Antibody‐Mediated Disease With Emerging Therapeutic Opportunities

Arthritis &Rheumatology, EarlyView.
Antiphospholipid syndrome (APS) is an autoimmune thromboinflammatory disease characterized by vascular thrombosis, pregnancy morbidity, and other manifestations driven by antiphospholipid autoantibodies. In this review, we present a clinical case that illustrates some diagnostic and therapeutic challenges in managing severe, relapsing APS ...
Thalia G. Newman, Jason S. Knight
wiley   +1 more source

Clinical Study on the Effects of Modified Hupo San on Reproductive Hormone Levels and Microcirculation in Patients with Menstrual Disorders of Cold Congelation and Blood Stasis Pattern. [PDF]

Int J Womens Health
Ma R, Zhang N, Xing J, Wang Y, Zhen X.
europepmc   +1 more source

Prognostic value of lupus anticoagulant and anti‐β2 glycoprotein I antibody in adverse pregnancy outcomes.

Arthritis &Rheumatology, Accepted Article.
Objective International criteria for antiphospholipid syndrome (APS) include lupus anticoagulant (LA), anticardiolipin (aCL) immunoglobulin (Ig) G and IgM, and anti‐β2‐glycoprotein I (β2GPI) IgG and IgM. However, evidence supporting their prognostic value or treatment efficacy in improving live birth rates is limited.
Megumi Nonobe, Takahiro Otani, Hiroyuki Yoshihara, Shinobu Goto, Tamao Kitaori, Naomi Nishikawa, Yuichiro Fujieda, Tatsuya Atsumi, Mayumi Sugiura‐Ogasawara   +8 more
wiley   +1 more source

Hypofibrinogenemia Following an Anaphylactic Shock Caused by a Neuromuscular Blocking Agent-Case Report. [PDF]

Case Rep Crit Care
Iarossi M, van de Wyngaert C, Hamoir V, Vanderweerden G, Hermans C.   +4 more
europepmc   +1 more source