Results 111 to 120 of about 11,652,656 (310)

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

Validation of the Medonic CA620/530 Vet 20-ml microcapillary sampler system for hematology testing of feline blood [PDF]

open access: yes, 2009
The aim of the current study was to compare feline hematologic variables in blood collected in microcapillary tubes (20 ml) and conventional blood tubes with the Medonic CA620/530 Vet in-house hematologic analyzer.
Geffré, Anne   +4 more
core  

Frequency of Pre-Analytical Errors and Its Causes in Glucose Specimen Collection: A Cross-Sectional Analysis in Bahawal Victoria Hospital, Pakistan

open access: yesPakistan Journal of Medicine and Dentistry
Background: The laboratory testing process comprises the pre-analytical, analytical, and post-analytical phases. The pre-analytical phase has the highest frequency of error among these three stages.
Hafiza Asma Hafiz   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Alexander Dalrymple, Esq., late hydrographer to the Admiralty [picture] /

open access: yes
Title from inscription below image.; Inscription: "Plate CCCCLVI ; engraved by Blood with the permifsion [i.e.permission] of the European Magazine from an original drawing by John Brown ; Alexander Dalrymple Esq., late hydrographer to the Admiralty ...
Blood, T., active 1814-1823.
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Clotting time analysis of citrated blood samples is strongly affected by the tube used for blood sampling [Elektronisk resurs]

open access: yes, 2005
Our aim was to establish whether differences in clotting times for recalcified blood and plasma samples might be explained by the use of different blood collection tubes.
Ramström, Sofia,
core  

Informationization and development strategy in blood collection and supply institutions in Beijing

open access: yes
[Objective] To investigate and analyze the current status, needs and issues of information system construction in blood collection and supply institutions in Beijing, and to provide strategic suggestions for the further improvements.
YUAN Yao   +5 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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